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X-Ray Diffraction and Fluorescence in the Analysis of Pharmaceutical Excipients

Published online by Cambridge University Press:  06 March 2019

A. J. Durbetaki  and
T. F. Quail
A. J. Durbetaki
Affiliation:
FMC Corporation, Chemical Research and Development Center, Princeton, New Jersey 08540
T. F. Quail
Affiliation:
FMC Corporation, Chemical Research and Development Center, Princeton, New Jersey 08540
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Extract

The majority of pharmaceutical dosage forms are marketed as tablets which are formulated to satisfy various basic requirements. The analysis of the resultant multicomponent pharmaceutical and product is usually a lengthy task.

This paper describes the complementary use of X-ray diffraction (XRD) and X-ray fluorescence spectroscopy (XRS) to characterize and quantify excipients in pharmaceutical tablets.

Type
VIII. XRD Applications
Information
Advances in X-Ray Analysis , Volume 25: Thirtieth Annual Conference on Applications of X-ray Analysis, August 3-7, 1981 , 1981 , pp. 383 - 388
Copyright
Copyright © International Centre for Diffraction Data 1981

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References

1 Wakelin, J. H.; Virgin, H. S. and Crystal, E., J. Appl. Phys. 30, 1654 (1959).Google Scholar
2 Criss, J. W.; Birks, L. S. and Gilfrich, J. V., Anal. Chem. 50, 73 (1978).Google Scholar