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Elemental Analysis of Biomedical Samples by Pixe

Published online by Cambridge University Press:  06 March 2019

J. A. Guffey
Affiliation:
University of Florida, Gainesville, Florida 32611
H. A. Van Rinsvelt
Affiliation:
University of Florida, Gainesville, Florida 32611
W. R. Adams
Affiliation:
University of Colorado Medical Center and General Rose Memorial Hospital, Denver, Colorado 80220
R. M. Sarper
Affiliation:
Emory University Medical School, Atlanta, Georgia 30332
Z. Karcioglu
Affiliation:
Emory University Medical School, Atlanta, Georgia 30332
R. W. Fink
Affiliation:
Georgia Institute of Technology, Atlanta, Georgia 30332
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Extract

The use of particle-induced X-ray emission (PIXE) analysis as a standard analytical tool in the study of trace elements is well known. In the present investigation, an attempt is made to correlate human diseases with the presence or absence of trace elements and/or the changes in their concentration in healthy and diseased tissues. If such correlations do actually exist, trace element analysis could certainly be used as a diagnostic tool for the early detection of diseases and there is considerable interest in such information.

Type
Note
Copyright
Copyright © International Centre for Diffraction Data 1977

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References

1. Johansson, Sven A. E. and. Johansson, Thomas B., Nucl. Instr. and Meth. 137, 473 (1976).Google Scholar
2. Trace Elements in Human Health and Disease, Vol. I and II, Ed. by Prasad, A.S. and Oberleas, D., Academic Press, New York, (1976).Google Scholar
3. Lear, R.D., Van Rinsvelt, H. A. and Adams, W.R., Adv. in X-Ray Anal. 19, 521 (1976), and Adv. in X-Ray Anal. 20, 403 (1977).Google Scholar
4. Van Rinsvelt, H.A., Lear, R.D. and Adams, W.R., Nucl. Instr. and Meth. 142, 171 (1977).Google Scholar
5. This work submitted for publication in Cancer Research.Google Scholar