The place of statistical techniques and the digital computer in analytical chemistry is clearly exemplified in the X-ray spectrograph laboratory. As the statistician is obsolete who uses only a desk calculator for his calculations in this era of rapidly changing technology and the need for increased productivity, so the X-ray man is severely handicapped who ignores the place of statistical techniques and associated digital computation in his work. For his calculations, the statistical X-ray analyst may choose from among the following: a small specialized computer designed as part of his X-ray equipment, a medium-size computer located in the laboratory building with the capacity to handle all the problems generated by the various analytical specialists, a time-sharing computer station which he shares with other analytical or testing sections of his main laboratory, or batch processing of his data by his company's computer center. Advanced types of desk calculators are now available which will permit rapid completion of some types of complex calculations, especially if they are set up in a systematic fashion. Careful study of an individual laboratory's problems will provide economic justification for the most appropriate type of computer calculation; the choice is dependent on many factors. This paper describes the advantages and disadvantages of the various computer systems for the X-ray spectrographer and the numerous statistical techniques which he may employ as an aid in hi? work. Statistics provide him with the tools to design his experiments, interpret his data, control the process which supplies his samples, improve sampling procedures, calibrate his X-ray equipment, perform theoretical studies, and calculate, correct, average, and evaluate his analyses. Digital computation provides him with an extraordinarily rapid means of making these calculations; in some cases, they are virtually impossible without computerization. Examples of analyses are described which are made practicable only by this combined statistical computerized approach. The accuracy and precision of computerized analyses are higher than for results obtained by the usual X-ray methods; analyst error is reduced to a minimum. The economics of present-day industrial life, especially applied to the analytical laboratory as a service organization, demand the most efficient possible operation of all analytical equipment. The X-ray laboratory presents an outstanding example of the need for statistical analysis and its associated digital-computer computation.