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An Energy Dispersive System for the Analysis of Trace Elements in Human Blood Serum

Published online by Cambridge University Press:  06 March 2019

P. S. Ong ,
P. K. Lund ,
C. E. Litton  and
B. A. Mitchell
P. S. Ong
Affiliation:
The University of Texas M. D. Anderson Hospital, Houston, Texas 77025
P. K. Lund
Affiliation:
The University of Texas M. D. Anderson Hospital, Houston, Texas 77025
C. E. Litton
Affiliation:
The University of Texas M. D. Anderson Hospital, Houston, Texas 77025
B. A. Mitchell
Affiliation:
The University of Texas M. D. Anderson Hospital, Houston, Texas 77025
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Abstract

A computerized systetn, consisting of a fluorescence x-ray source (Philips), an Si (Li) detector (Ortec), and a mini Computer (Xerox) is currentiy in operation at The University of Texas M. D. Anderson Hospital and Tumor Institute, Experimentel Pathology Section, for the analysis of trace elements in biological specimens. The elements of interest are Fe, Cu, and Zn for possible significance in the detection and study of cancer. The detection system is being used for comparatively routine analysis of these elements, which are present in blood serum in the ppM range. With appropriate sample preparation techniques, using 1 ml of serum, the limit of detectability for these elements is estimated to be 100 ppB (1 in 107). Further refinement is possible, and research in this direction continues.

Type
Research Article
Information
Advances in X-Ray Analysis , Volume 16: 'Twenty-First Annual Conference on Applications of X-ray Analysis, August 2-4, 1972 , 1972 , pp. 124 - 133
Copyright
Copyright © International Centre for Diffraction Data 1972

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