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Simulating samples from a genetic population

Published online by Cambridge University Press:  01 July 2016

G. A. Watterson
G. A. Watterson*
Affiliation:
Monash University, Clayton, Victoria
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Extract

Consider a genetic population evolving in time. In particular, suppose that the population is very large, that there is a large number of genetic types (alleles) possible for the genes making up the population, and that the numbers of the various alleles change stochastically in time, subject to Mendel's law of inheritance. Assume that there are no selective differences among the genotypes, but that mutation may occur among the alleles.

Type
Research Article
Information
Advances in Applied Probability , Volume 10 , Issue 4 , December 1978 , pp. 720 - 723
Copyright
Copyright © Applied Probability Trust 1978 

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References

Ewens, W. J. (1972) The sampling theory of selectively neutral alleles. Theoret. Popn. Biol. 3, 87–112.Google Scholar
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Kirby, K. (1975) A discussion of simulation results for various aspects of the neutral allele model. Theoret. Popn. Biol. 7, 277–287.CrossRefGoogle Scholar
Watterson, G. A. (1978) The homozygosity test of neutrality. Genetics 88, 405–417.Google Scholar