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The infinitely-many-neutral-alleles diffusion model by ages

Published online by Cambridge University Press:  01 July 2016

S. N. Ethier*
Affiliation:
University of Utah
*
Postal address: Department of Mathematics, University of Utah, Salt Lake City, UT 84112, USA. E-mail address: [email protected]

Abstract

We discuss two formulations of the infinitely-many-neutral-alleles diffusion model that can be used to study the ages of alleles. The first one, which was introduced elsewhere, assumes values in the set of probability distributions on the set of alleles, and the ages of the alleles can be inferred from its sample paths. We illustrate this approach by proving a result of Watterson and Guess regarding the probability that the most frequent allele is oldest. The second diffusion model, which is new, assumes values in the set of probability distributions on the set of pairs (x, a), where x is an allele and a is its age. We illustrate this second approach by proving an extension of the Ewens sampling formula to age-ordered samples due to Donnelly and Tavaré.

Type
Research Article
Copyright
Copyright © Applied Probability Trust 1990 

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Footnotes

Research supported in part by NSF grant DMS-8704369.

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