Hostname: page-component-cd9895bd7-gbm5v Total loading time: 0 Render date: 2024-12-22T23:08:02.876Z Has data issue: false hasContentIssue false
  • English
  • Français

Treating depression with sleep deprivation and consecutive sleep phase advance therapy

Published online by Cambridge University Press:  18 September 2015

M. Berger ,
J. Vollmann ,
F. Hohagen ,
A. König ,
H. Lohner  and
D. Riemann
Get access Rights & Permissions [Opens in a new window]

Extract

The common treatment modalities for depression, i.e. pharmacotherapy and psychotherapy have the significant disadvantage of at least a three- to four-week time lag between initiation of treatment and amelioration of mood. Total sleep deprivation (TSD) in contrast, leads to an immediate antidepressant effect in 60% of the patients. However, it has gained only little clinical relevance as usually the improvement is only transient and almost regularly reversed by the next nights of sleep. A procedure preserving the antidepressive effect of sleep deprivation would therefore be of high clinical relevance.

Keywords

total sleep deprivationslaup-wake cyclephase advancemoodtotale slaapdeprivatieslaap-waak afwisselingfase verschuivingstemming
Type
Research Article
Information
Acta Neuropsychiatrica , Volume 7 , Issue 2 , June 1995 , pp. 50 - 51
Copyright
Copyright © Scandinavian College of Neuropsychopharmacology 1995

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Literature

1.Wu, JC, Bunney, WE. The biological basis of an antidepressant response to sleep deprivation and relapse: Review and hypothesis. Am J Psychiat 1990; 147: 14–21.Google ScholarPubMed
2.Van den Hoofdakker, RH, Beersma, DGM. On the contribution of sleep wake physiology to the explanation and treatment of depression. Acta psychiat scand 1988; 341:53–71.CrossRefGoogle Scholar
3.Vollmann, J, Berger, M. Sleep deprivation with consecutive sleep-phase advance therapy in patients with major depression: A pilot study. Biol Psychiat 1993; 33: 54–7.CrossRefGoogle ScholarPubMed
4.Wiegand, M, Riemann, D, Schreiber, W, Lauer, CJ, Berger, M. Effect of morning and afternoon naps on mood after total sleep deprivation in patients with major depression. Biol Psychiat 1993; 33: 467–76.CrossRefGoogle ScholarPubMed
5.Wehr, TA, Wirz-Justice, A, Goodwin, FK. Phase advance of the circadian sleep cycle as an antidepressant. Science 1979; 206:710–3.CrossRefGoogle ScholarPubMed
6.Souêtre, E, Salvati, E, Candito, M, Darcourt, G. Biological clocks in depression: Phaseshift experiments revisited. Eur Psychiat 1991; 6: 21–9.CrossRefGoogle Scholar