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Published online by Cambridge University Press: 18 September 2015
Human immuno deficiency virus may cause a broad spectrum of psychiatric sequelae. In this review we discus the possible associations between HIV infection with psychosis, mild neurocognitive disorder and dementia. The cerebral reserve model gives an explanation why HIV infected individuals with low educational level and/or intravenous drug users are more vulnerable to direct and indirect neurotoxic effects of HIV.