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Monoamines and CSF: relevance to neuropsychiatric disorders

Published online by Cambridge University Press:  18 September 2015

W.M.A. Verhoeven
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Summary

Over the past 25 years much effort has been put into the research of the relationship between neuropsychiatric disorders and the concentrations of CSF-monoamine metabolites. Most of this research has beenfocused on the relation between CSF-concentrations of 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) and specific symptomatological entities, particularly schizophrenia, Alzheimer's dementia and endogenous depression. It appeared that specific relations between diseases and CSF-concentrations of monoamine metabolites cannot be longer maintained and that a more functional psychopathology should be considered as the future research strategy.

Keywords

DementiadepressionschizophreniaHVA5-HIAACSFDementiedepressieschizofrenieHVZ5-HIAZliquor
Type
Research Article
Information
Acta Neuropsychiatrica , Volume 4 , Issue 3 , September 1992 , pp. 47 - 51
Copyright
Copyright © Scandinavian College of Neuropsychopharmacology 1992

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