Hostname: page-component-586b7cd67f-t7fkt Total loading time: 0 Render date: 2024-11-23T07:05:36.676Z Has data issue: false hasContentIssue false

Melatonin: hormone of the night

Published online by Cambridge University Press:  24 June 2014

Trevor R. Norman*
Affiliation:
Department of Psychiatry, University of Melbourne, Austin Hospital, Heidelberg 3084, Victoria, Australia
*
Associate Professor Trevor R. Norman Department of Psychiatry, University of Melbourne, Austin Hospital, Heidelberg 3084, Victoria, Australia. Tel: +61 3 94965511; Fax: +61 3 9459 0821; E-mail: [email protected]

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Intervention Insights
Copyright
Copyright © 2009 John Wiley & Sons A/S

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Hardeland, R, Fuhrberg, B.Ubiquitous melatonin. Presence and effects in unicells, plants and animals. Trends Comp Biochem Physiol 1996;2:2545. Google Scholar
Pandi-Perumal, SR, Srinivasan, V, Maestroni, GJ, Cardinali, DP, Poeggeler, B, Hardeland, R.Melatonin: nature's most versatile biological signal? FEBS J 2006;273:28132838. CrossRefGoogle ScholarPubMed
Claustrat, B, Brun, J, Cazot, G.The basic physiology and pathophysiology of melatonin. Sleep Med Rev 2005;9:1124. CrossRefGoogle ScholarPubMed
Yu, H-S, Tsin, ATC, Reiter, RJ.Melatonin: History, biosynthesis and assay methodology. In: Yu, H-S, Reiter, R.J., eds. Melatonin: biosynthesis, physiological effects and clinical applications. Boca Raton: CRC Press, 1993;116. Google Scholar
Dubocovich, ML, Markowska, M.Functional MT1 and MT2 receptors in mammals. Endocrine 2005;27:101110. CrossRefGoogle ScholarPubMed
Lewy, AJ, Emens, JS, Lefler, BJ, Yuhas, K, Jackman, AR.Melatonin entrains free-running blind people according to a physiological dose response curve. Chronobiol Int 2005;22:10931106. CrossRefGoogle ScholarPubMed
Herxheimer, A, Petrie, KJ.Melatonin for the prevention and treatment of jet lag. Cochrane Database Syst Rev 2008;(1) CD001520. Google ScholarPubMed
Rodrigeuz, C, Mayo, JC, Sainz, RMet al. Regulation of antioxidant enzymes: a significant role for melatonin. J Pineal Res 2004;36:19. CrossRefGoogle Scholar
Germain, A, Kupfer, DJ.Circadian rhythm disturbances in depression. Hum Psychopharmacol 2008;23:571585. CrossRefGoogle ScholarPubMed
Beck-Fdriis, J, Kjellerman, BF, Aperia, B.et al. Serum melatonin in relation to clinical variables in patients with major depressive disorder and a hypothesis of low melatonin syndrome. Acta Psychiatr Scand 1985;71:319330. CrossRefGoogle Scholar
Thompson, C, Mezey, G, Corn, Tet al. The effect of desipramine upon melatonin and cortisol secretion in depressed and normal subjects. Br J Psychiatry 1985;147:389393. CrossRefGoogle ScholarPubMed
McIntyre, IM, Norman, TR, Burrows, GD, Armstrong, SM.Alterations to plasma melatonin and cortisol after evening alprazolam administration. Chronbiol Int 1993;10:205213. CrossRefGoogle ScholarPubMed
McIntyre, IM, Norman, TR, Burrows, GD, Armstrong, SM.Human melatonin suppression by light is intensity dependent. J Pineal Res 1969;6:149156. CrossRefGoogle Scholar
Nathan, PJ, Burrows, GD, Norman, TR.Melatonin sensitivity to din white light in affective disorders. Neuropsychopharmacol 1999;21:408413. CrossRefGoogle Scholar
Hallam, KT, Olver, JS, Horgan, JE, McGrath, C, Norman, TR.Low doses of lithium carbonate reduce melatonin light sensitivity in healthy volunteers. Int J Neuropsychopharmacol 2004;8:15. Google ScholarPubMed
Hallam, KT, Olver, JS, Norman, TR.Effect of sodium valproate on nocturnal melatonin sensitivity to light in healthy volunteers. Neuropsychopharmacology 2005;30:14001404. Google ScholarPubMed
Zhdanova, IV, Tucci, V.Melatonin circadian rhythms and sleep. Curr Treat Options Neurol 2003;5:225229. CrossRefGoogle ScholarPubMed
Wirz-Justice, A.Biological rhythms and depression: Treatment opportunities. WPA Bulletin on Depression 2008;13:59. Google Scholar
Lemoine, P, Nir, T, Laudon, M, Zisapel, N.Prolonged release melatonin improves sleep quality and morning alertness in insomnia patients aged 55 years and older and has no withdrawal effects. J Sleep Res 2007;16:372380. CrossRefGoogle ScholarPubMed
Wade, AG, Ford, I, Crawford, Get al. Efficacy of prolonged release melatonin in insomnia patients aged 55–80 years: Quality of sleep and next day alertness outcomes. Curr Med Res Opin 2007;23:25972605. CrossRefGoogle ScholarPubMed
Haffmans, PM, Sival, RC, Lucius, SA, Cats, Q, Van Gelder, L.Bright light therapy and melatonin in motor restless behaviour in dementia: a placebo-controlled study. Int J Geriatr Psychiatry 2001;16:106110. 3.0.CO;2-9>CrossRefGoogle ScholarPubMed
Cardinali, DP, Brusco, LI, Liberczuk, C, Furio, AM.The use of melatonin in Alzheimer's disease. Neuro Endocinol Lett 2002;23(Suppl. 1):2023. Google Scholar