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Magneto-encefalografie

Published online by Cambridge University Press:  18 September 2015

M.J. Peters  and
F. Reinders
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Summary

A magnetoencephalogram (MEG) is the registration of the magnetic field in points near the head. Because MEG's are weak fields, they have to be measured by means of superconducting sensors. The electric active population of neurons can be computed from the distribution of the magnetic field at a certain instant of time. This is called the inverse problem. In order to solve this probem, both the generators and the head have to be modelled. Usually, a patch of active neurons is modelled as a current dipole. Commonly, the head is described by three compartments, representing the brain, the skull and the scalp. The compartments may have the shape of spheres or they may have a realistic shape. Integration of EEG and MEG with MRI leads to a technique for functional imaging of the brain with a time resolution of one millisecond and a spatial resolution of one centimetre. Clinical applications are the non-invasive localization of an epileptic focus or the presurgical mapping of the sensorimotor cortex.

Keywords

Magnetoencephalographyelectroencephalographyfunctional imagingneuromagnetometerMagneto-encefalografieelektro-encefalografiefunctional imagingneuromagnetometer
Type
Research Article
Information
Acta Neuropsychiatrica , Volume 8 , Issue 3 , September 1996 , pp. 64 - 70
Copyright
Copyright © Scandinavian College of Neuropsychopharmacology 1996

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References

Literatuur

1.Broca, P. Sur la faculté du langaga articulé. Bull soc Anthropol (Parijs) 1865; 6: 337–93.Google Scholar
2.Glickstein, M. The discovery of the visual cortex. Sci Am 1988; 08: 84–91.Google ScholarPubMed
3.Orrison, WW, Lewine, JD, Sanders, JA, Hartshorne, MF, eds. Functional Brain Imaging. St. Louis: Mosby Publ, 1995.Google Scholar
4.Wieringa, HJ, Peters, MJ. Processing MRI data for electromagnetic source imaging. Med Biol Eng Comput 1993; 31: 600–6.CrossRefGoogle ScholarPubMed
5.Meijs, JWH. The influence of head geometries on electro- and magnetoencephalograms. Enschede: University of Twente, The Netherlands, 1988: Thesis.Google Scholar
6.Zanow, F, Peters, MJ. Individually shaped volume conductor models of the head in EEG source localization. Med Biol Eng Comput 1995; 33: 582–8.CrossRefGoogle Scholar
7.Stefan, H, Schneider, S, Abraham-Fuchs, K, et al.The neocortico mesio-basal limbic propagation of focal epileptic activity during the spike-wave complex. Electroencephal clin Neurophysiol 1991; 79: 1–10.CrossRefGoogle ScholarPubMed
8.Paetau, R, Kajola, M, Karhu, Jet al.MEG localization of epileptic cortex- Impact on surgical treatment. Ann Neurol 1992; 32: 106–9.CrossRefGoogle Scholar
9.Lewine, JD, Orrison, WW, Astur, RS, Davis, LE, Knight, JE, Maclin, EL, Reeve, A. Explorations of pathophysiological spontaneous activity by magnetic source imaging. In: Baumgartner, Cet al, eds. Biomagnetism: Fundamental Research and Clinical Applications. Amsterdam: Elsevier Science IOS Press, 1995: 55–9.Google Scholar
10.Orrison, WW, Lewine, JD. Magnetic source imaging in neurosurgical practise. Perspect Neurol Surg 1993; 4: 141–8.Google Scholar
11.Gallen, CC, Sobel, DF, Waltz, T and al. Noninvasive pre-surgical neuromagnetic mapping of somatosensory cortex. Neurosurgery 1993; 33: 260–8.CrossRefGoogle Scholar
12.Romani, Gl, Williamson, SJ, Kaufman, L. Tonotopic organization of the human auditory cortex. Science 1982; 216: 1339–40.CrossRefGoogle ScholarPubMed
13.Ebersole, J, Squires, K, Gamelin, J, Lewine, J. and Scherg, M. Dipole models of temporal lobe spikes from simultaneous MEG and EEG. In: Baumgartner, Cet al, eds. Biomagnetism: Fundamental Research and Clinical Applications. Amsterdam: Elsevier Science IOS Press, 1995: 20–2.Google Scholar