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Induced psychosis after withdrawal of varenicline: a case report

Published online by Cambridge University Press:  24 June 2014

María T. López Arteaga*
Affiliation:
Department of Psychiatry, Hospital Universitario de Guadalajara, Guadalajara, Spain
Carlos Amo
Affiliation:
Department of Psychiatry, Hospital Universitario de Guadalajara, Guadalajara, Spain
Eva M. Sánchez Morla
Affiliation:
Department of Psychiatry, Hospital Universitario de Guadalajara, Guadalajara, Spain
Marina Sánchez Román
Affiliation:
Department of Psychiatry, Hospital Universitario de Guadalajara, Guadalajara, Spain
*
María Teresa López Arteaga, Department of Psychiatry, Hospital Universitario de Guadalajara, C/ Donante de sangre S/N, 19002 Guadalajara, Spain. Tel: +34 949 209 200; Fax: +34 949 209 218; E-mail: [email protected]

Extract

López Arteaga MT, Amo C, Sánchez Morla EM, Sánchez Román M. Induced psychosis after withdrawal of varenicline: a case report.

Objective: Varenicline has been associated with psychiatric side effects, and cases with psychotic symptoms during treatment have been reported, few of them after the withdrawal. We describe a case with no current or previous medical or psychiatric history.

Method: A single case report.

Results: The patient without previous psychiatric pathology, following the withdrawal of treatment with varenicline, experiences delirium and behavioural disturbances. There was a remission of symptoms after 3 weeks of treatment with risperidone.

Conclusion: Discontinuation of treatment with varenicline due to poor tolerance for side effects (nausea and insomnia) could trigger psychotic symptoms in subjects with no personal or family psychiatric history.

Type
Case Reports
Copyright
Copyright © Cambridge University Press 2011

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