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Focal neurocognitive dysfunctions in abstinence delirium: a case report

Published online by Cambridge University Press:  18 September 2015

P. Mariën ,
F. Borggreve ,
W. Spanoghe ,
J. Saerens ,
B.A. Pickut  and
P.P. De Deyn
P. Mariën*
Affiliation:
Departement Neurologie en Nucleaire Geneeskunde Algemeen Ziekenhuis Middelheim, Antwerpen
F. Borggreve
Affiliation:
Departement Neurologie en Nucleaire Geneeskunde Algemeen Ziekenhuis Middelheim, Antwerpen
W. Spanoghe
Affiliation:
Departement Neurologie en Nucleaire Geneeskunde Algemeen Ziekenhuis Middelheim, Antwerpen
J. Saerens
Affiliation:
Departement Neurologie en Nucleaire Geneeskunde Algemeen Ziekenhuis Middelheim, Antwerpen
B.A. Pickut
Affiliation:
Departement Neurologie en Nucleaire Geneeskunde Algemeen Ziekenhuis Middelheim, Antwerpen Nucleaire Geneeskunde Algemeen Ziekenhuis Middelheim, Antwerpen
P.P. De Deyn
Affiliation:
Departement Neurologie en Nucleaire Geneeskunde Algemeen Ziekenhuis Middelheim, Antwerpen Departement Neurologie, Born-Bunge Instituut, Laboratorium Neurochemie en Gedrag, Universiteit Antwerpen
*
A.Z. Middelheim, Dienst Neurologie, Lindendreef 1, B-2020 Antwerpen, België
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Summary

Due to abrupt interruption of hidden benzodiazepine-use, a 68-year-old woman developed a full-blown abstinence delirium characterized by epileptic seizures and progressive focal neurocognitive symptoms. The evolution of such rare neuro-linguistic phenomena as an echoism, palilalia and glossomania associated with a progressive visuo-perceptive syndrome and a visual hallucinosis are for the first time reported within the context of withdrawal. Notwithstanding the lack of any neuroradiological evidence for a morphological lesion in the clinically expected brain regions, the anatomo-clinical hypothesis of a focal frontal and parieto-occipital dysfunction was explicitly corroborated by repeated 99mTc-HMPAO SPECT findings.

Keywords

Benzodiazepinesabstinence deliriumneuropsychologyfocal dysfunctionsvisual hallucinosispalilaliaglossomania99mTc-HMPAO SPECTBenzodiazepinenabstinentiedeliriumneuropsychologic focale dysfunctiesvisuele hallucinosepalilalieglossomanie99mTc-HMPAO SPECT
Type
Research Article
Information
Acta Neuropsychiatrica , Volume 9 , Issue 3 , September 1997 , pp. 107 - 115
Copyright
Copyright © Scandinavian College of Neuropsychopharmacology 1997

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