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Dysregulation of ion fluxes in bipolar affective disorder
Published online by Cambridge University Press: 18 September 2015
Abstract
Bipolar disorder has attracted numerous research from different neurobiological angles. This review will summarize selected findings focusing on the role of disturbed transmem-braneous ion fluxes. Several mood stabilizers exhibit a distinct profile including effects on sodium, calcium and potassium conductance. In summary, some decisive mechanisms of action as calcium antagonism and modulation of potassium currents may play a crucial role in the success of any given mood stabilizer in bipolar disorder.
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- Copyright © Scandinavian College of Neuropsychopharmacology 2000
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