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Daytime sleepiness, sleep disturbance and functioning impairment in bipolar disorder

Published online by Cambridge University Press:  21 February 2013

Julio C. Walz ,
Pedro V. Magalhães ,
Ramiro Reckziegel ,
Monise Costanzi ,
Larriany Giglio  and
Flávio Kapczinski
Julio C. Walz
Affiliation:
Bipolar Disorders Program & INCT Translational Medicine, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil Centro Universitário La Salle Canoas, Canoas, Brazil
Pedro V. Magalhães
Affiliation:
Bipolar Disorders Program & INCT Translational Medicine, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil Centro Universitário La Salle Canoas, Canoas, Brazil
Ramiro Reckziegel
Affiliation:
Bipolar Disorders Program & INCT Translational Medicine, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
Monise Costanzi
Affiliation:
Bipolar Disorders Program & INCT Translational Medicine, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
Larriany Giglio
Affiliation:
Bipolar Disorders Program & INCT Translational Medicine, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
Flávio Kapczinski*
Affiliation:
Bipolar Disorders Program & INCT Translational Medicine, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
*
Professor Flávio Kapczinski, Laboratório de Psiquiatria Molecular, Hospital de Clinicas de Porto Alegre (HCPA), Ramiro Barcelos, 2350, CEP 90035‐003, Porto Alegre, RS, Brazil. Tel: +55 51 21018845; Fax: +55 51 21018846; E‐mail: [email protected]
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Abstract

Objective

To verify the prevalence and clinical impact of excessive daytime sleepiness (EDS) in outpatients with bipolar disorder.

Methods

Eighty‐one outpatients with bipolar disorder and 79 healthy control subjects were recruited. Patients were required not to be acutely manic or depressed. We used the Epworth Sleepiness Scale, the Pittsburgh Sleep Quality Index and the Functioning Assessment Short Test to assess sleepiness, sleep problems and functioning, respectively.

Results

Patients had a higher prevalence of sleepiness (40%) than the control group (18%). Sleepiness and sleep disturbance had independent impacts on disability in the multivariable model.

Conclusions

This study suggests that EDS is a relevant clinical dimension in patients with bipolar disorder. It is a frequent symptom that often overlaps with other sleep disturbances. This study also reveals that once present it has the potential to increase functional impairment.

Keywords

bipolar disorderdisabilityfunctioningsleep disorderssleepiness
Type
Original Articles
Information
Acta Neuropsychiatrica , Volume 25 , Issue 2 , April 2013 , pp. 101 - 104
Copyright
Copyright © Scandinavian College of Neuropsychopharmacology 2013

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