Hostname: page-component-cd9895bd7-dzt6s Total loading time: 0 Render date: 2025-01-03T14:43:32.415Z Has data issue: false hasContentIssue false
  • English
  • Français

Conduct disorders and an abnormal sex-chromosomal pattern

Published online by Cambridge University Press:  18 September 2015

A.M.S. Thomaes  and
W.M.A. Verhoeven
A.M.S. Thomaes*
Affiliation:
Vincent van Gogh Instituut, Venray
W.M.A. Verhoeven
Affiliation:
Vincent van Gogh Instituut, Venray
*
Vincent van Gogh Instituut voor Psychiatrie, Postbus 5, 5800 AA Venray
Get access Rights & Permissions [Opens in a new window]

Summary

Two subjects are described suffering from longlasting behavioral disorders, who appeared to have both an abnormal karyotype, 47XXY and 47XYY respectively. The relationship between psychopathological disorders and the type of karyotypes is discussed. It is concluded that both biological and environmental factors are involved in the development of behavioral disorders that are observed frequently in this kind of subjects.

Keywords

47XXY karyotype47XYY karyotypebehavorial disordersbiological vulnerability47XXY chromosomenpatroon47XYY chro-mosomenpatroongedragsstoornissenbiologische kwetsbaarheid
Type
Research Article
Information
Acta Neuropsychiatrica , Volume 5 , Issue 1 , March 1993 , pp. 15 - 18
Copyright
Copyright © Scandinavian College of Neuropsychopharmacology 1993

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Literatuur

1.Jacobs, PA, Price, WH, Court Brown, WM, Brittain, RP, Whatmore, PB. Chromosome studies on men in a maximum security hospital. Ann hum Genet 1968; 31; 339-58.CrossRefGoogle Scholar
2.Jacobs, PA. XYY Genotype, Science 1975; 189: 1044-5.CrossRefGoogle ScholarPubMed
3.Rouwet, JG, Hustinx, TWJ. Het 47 XYY chromosomenpatroon bij de mens. Maandschr Kindergeneesk 1970; 38: 238-43.Google Scholar
4.Moore, KL. The Developing Human: Clinically Oriented Embryology. Philadelpia, London, Toronto: WB Saunders, 1977: 124-30, 247.Google Scholar
5.German, J. Cytogenetic aspects of human disease. In: Petersdorf, RG, Adams, RD, Braunwald, E, Isselbacher, KJ, Martin, JB, Wilson, JD, red. Harrison's Principles of Internal Medicine. Auckland: Mc Graw-Hill, 1983: 333-9.Google Scholar
6.Wilson, JD, Griffin, JE. Disorders of chromosomal Sex. In: Petersdorf, RG, Adams, RD, Braunwald, E, Isselbacher, KJ, Martin, JB, Wilson, JD, red. Harrison's Principles of Internal Medicine. Auckland: Mc Graw-Hill, 1983: 726-7.Google Scholar
7.Nielsen, J, Wohlert, M. Sex chromosome abnormalities found among 34.910 newborn childeren: results from a 13 year incidence study in Arhus, Denmark. Birth Defects: Original article series, 1991;26:209-23.Google Scholar
8.Kleczlowska, A, Fryns, JP, Berghe van den, H. X-chromosome polysomy in the male. Hum Genet 1988; 80: 16–22.CrossRefGoogle Scholar
9.König, MP. Befund: kleine Hoden. Schweiz med Wochenschr 1987; 117: 731-5.Google Scholar
10.Grass, F, MC Combs, J, Scott, DR, Young, RS, Moore, CM. Reproduction in XYY males. Am J med Genet, 1984; 19: 553-60.CrossRefGoogle ScholarPubMed
11.Lishman, WA, Klinefelters syndrome. In: Lishman, WA. Organic Psychiatry. The psychological consequences of cerebral disorder. Sec ed. London: Blackwell Sci Publ, 1987: 465-70.Google Scholar
12.Nielsen, J, Sillesen, I, Sorensen, AMet al.Follow-up until age 4 to 8 of 25 unselected children with sex chromosome abnormalities compared with sibs and controls. Birth Defects 1979; 15: 15–73.Google ScholarPubMed
13.Nielsen, J. Sillesen, I. Incidence of chromosome abberations among 11148 new-born children. Hum Genet 1975; 30: 1–12CrossRefGoogle Scholar
14.Mandoki, MW, Sumner, GS. Klinefelter syndrome: the need for early identification and treatment. Clin Ped 1991; 30: 161-4.CrossRefGoogle ScholarPubMed
15.Nielsen, J, Pelsen, B. Follow-up 20 yaers later of 34 Klinefelter males with karyotype,XXY and 16 hypogonadal males with karyotype 46,XY. Hum Genet 1987; 77: 188-92.CrossRefGoogle Scholar
16.Schiavi, RC, Thielgaard, A, Owen, DR, White, D. Sex chromosome anomalies, hormones and sexuality. Arch gen Psych 1988; 45: 19–24.CrossRefGoogle ScholarPubMed
17.Owen, DR. Psychological studies in XYY men. In: Owen, DR. Genetic mechanisms of sexual develoment. New York: Academic Press, 1979: 465-70.Google Scholar
18.Schiavi, RC. Sex chromosomes anomalies, hormones and aggressivity. Arch gen Psych 1984; 47: 93-9.CrossRefGoogle Scholar