Hostname: page-component-cd9895bd7-lnqnp Total loading time: 0 Render date: 2024-12-23T19:49:07.689Z Has data issue: false hasContentIssue false
  • English
  • Français

Cigarette smoking, coffee intake and alcohol consumption preceding Parkinson's disease: a case–control study

Published online by Cambridge University Press:  24 June 2014

Sandra B. Sipetic ,
Hristina D. Vlajinac ,
Jadranka M. Maksimovic ,
Jelena M. Marinkovic ,
Eleonora D. Dzoljic ,
Isidora S. Ratkov  and
Vlada S. Kostic
Sandra B. Sipetic
Affiliation:
Institute of Epidemiology, Faculty of Medicine, Belgrade University, Belgrade, Serbia
Hristina D. Vlajinac*
Affiliation:
Institute of Epidemiology, Faculty of Medicine, Belgrade University, Belgrade, Serbia
Jadranka M. Maksimovic
Affiliation:
Institute of Epidemiology, Faculty of Medicine, Belgrade University, Belgrade, Serbia
Jelena M. Marinkovic
Affiliation:
Institute of Medical Statistics and Informatics, Faculty of Medicine, Belgrade University, Belgrade, Serbia
Eleonora D. Dzoljic
Affiliation:
Institute of Neurology, Faculty of Medicine, Belgrade University, Belgrade, Serbia
Isidora S. Ratkov
Affiliation:
Institute of Epidemiology, Faculty of Medicine, Belgrade University, Belgrade, Serbia
Vlada S. Kostic
Affiliation:
Institute of Neurology, Faculty of Medicine, Belgrade University, Belgrade, Serbia
*
Hristina D. Vlajinac, Institute of Epidemiology, Faculty of Medicine, Belgrade University, Visegradska 26, 11000 Belgrade, Serbia. Tel: +381113607064; Fax: +381113607062; E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Extract

Objective: A case–control study was performed in Belgrade in order to investigate the association between Parkinson's disease (PD) and smoking, coffee and alcohol consumption.

Methods: During the period 2001–2005, 110 new PD cases and 220 hospital controls were interviewed. Cases and controls were matched by sex, age and place of residence (urban/rural). For the analysis of data conditional univariate and multivariate logistic regression methods were used.

Results: With PD were associated, independently from each other, current smoking [odds ratio (OR) = 0.44; 95% confidence interval (CI) = 0.23–0.82], alcohol consumption (OR = 4.78; 95% CI = 2.67–8.55) and coffee consumption (OR = 2.54; 95% CI = 1.36–4.75). In ever smokers the risk for PD significantly decreased with the increasing number of cigarettes smoked and with increasing duration of smoking. The risk for PD significantly increased with the increasing quantity of alcohol consumption. PD risk was significantly higher in subjects whose average daily consumption of coffee was 1 and 2–3 cups, and it was lower (but not significantly) in those whose daily coffee consumption was 4+ cups. Cases and controls did not differ in duration of alcohol and coffee consumption. The results of multivariate analyses did not substantially change after adjustment on family history positive on PD.

Conclusion: The findings of this study support the hypotheses of inverse association of smoking with PD, but an inverse association with coffee was not confirmed. PD was found to be positively associated with coffee and alcohol consumption.

Keywords

alcohol consumptioncase–control studycigarette smokingcoffee intakeParkinson's disease
Type
Research Article
Information
Acta Neuropsychiatrica , Volume 24 , Issue 2 , April 2012 , pp. 109 - 114
Copyright
Copyright © Cambridge University Press 2011

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Kontakos, N, Stokes, J.Monograph series on aging-related diseases: XII. Parkinson's disease - recent developments and new directions. Chronic Dis Can 1999;20:58–76.Google ScholarPubMed
2.Gorell, JM, Peterson, EL, Rybicki, BA, Johnson, CC.Multiple risk factors for Parkinson's disease. J Neurol Sci 2004;217:169–174.CrossRefGoogle ScholarPubMed
3.Logroscino, G.The role of early life environmental risk factors in Parkinson disease: what is the evidence? Environ Health Perspect 2005;113:1234–1238.CrossRefGoogle ScholarPubMed
4.Hernán, MA, Takkouche, B, Caamaño-Isorna, F, Gestal-Otero, JJ.A meta-analysis of coffee drinking, cigarette smoking, and the risk of Parkinson's disease. Ann Neurol 2002;52:276–284.CrossRefGoogle ScholarPubMed
5.Checkoway, H, Powers, K, Smith-Weller, T, Franklin, GM, Longstreth, WT Jr., Swanson, PD.Parkinson's disease risks associated with cigarette smoking, alcohol consumption, and caffeine intake. Am J Epidemiol 2002;155: 732–738.CrossRefGoogle ScholarPubMed
6.Dong, JQ, Zhang, ZX, Zhang, KL.Parkinson's disease and smoking: an integral part of PD's etiological study. Biomed Environ Sci 2003;16:173–179.Google ScholarPubMed
7.Benedetti, MD, Bower, JH, Maraganore, DM et al. Smoking, alcohol, and coffee consumption preceding Parkinson's disease: a case-control study. Neurology 2000; 55:1350–1358.CrossRefGoogle ScholarPubMed
8.Ragonese, P, Salemi, G, Morgante, L et al. A case-control study on cigarette, alcohol, and coffee consumption preceding Parkinson's disease. Neuroepidemiology 2003;22:297–304.CrossRefGoogle ScholarPubMed
9.Tan, EK, Tan, C, Fook-Chong, SM et al. Dose-dependent protective effect of coffee, tea, and smoking in Parkinson's disease: a study in ethnic Chinese. J Neurol Sci 2003;216: 163–167.CrossRefGoogle ScholarPubMed
10.Ascherio, A, Weisskopf, MG, O'Reilly, EJ et al. Coffee consumption, gender, and Parkinson's disease mortality in the cancer prevention study II cohort: the modifying effects of estrogen. Am J Epidemiol 2004;160:977–984.CrossRefGoogle ScholarPubMed
11.Ross, GW, Abbott, RD, Petrovitch, H et al. Association of coffee and caffeine intake with the risk of Parkinson disease. JAMA 2000;283:2674–2679.CrossRefGoogle ScholarPubMed
12.Ascherio, A, Zhang, SM, Hernán, MA et al. Prospective study of caffeine consumption and risk of Parkinson's disease in men and women. Ann Neurol 2001;50:56–63.CrossRefGoogle ScholarPubMed
13.Fall, PA, Fredrikson, M, Axelson, O, Granérus, AK.Nutritional and occupational factors influencing the risk of Parkinson's disease: a case-control study in southeastern Sweden. Mov Disord 1999;14:28–37.3.0.CO;2-O>CrossRefGoogle ScholarPubMed
14.Hernán, MA, Chen, H, Schwarzschild, MA, Ascherio, A.Alcohol consumption and the incidence of Parkinson's disease. Ann Neurol 2003;54:170–175.CrossRefGoogle ScholarPubMed
15.Fahn, S, and the members of the UPDRS Development Committee. Unified Parkinson's disease rating scale. In: Fahn, S, Marsden, CD, Goldstein, M, Calne, DB, eds. Recent development in Parkinson's disease, Vol. 2. Florham Park: MacMillan, 1987: 153–163.Google Scholar
16.Chan, DK, Woo, J, Ho, SC et al. Genetic and environmental risk factors for Parkinson's disease in a Chinese population. J Neurol Neurosurg Psychiatry 1998;65:781–784.CrossRefGoogle ScholarPubMed
17.Ma, L, Zhang, L, Gao, XH et al. Dietary factors and smoking as risk factors for PD in a rural population in China: a nested case-control study. Acta Neurol Scand 2006;113:278–281.CrossRefGoogle Scholar
18.Tzourio, C, Rocca, WA, Breteler, MM et al. Smoking and Parkinson's disease. An age-dependent risk effect? The EUROPARKINSON Study Group. Neurology 1997;49: 1267–1272.CrossRefGoogle ScholarPubMed
19.Wirdefeldt, K, Gatz, M, Pawitan, Y, Pedersen, NL.Risk and protective factors for Parkinson's disease: a study in Swedish twins. Ann Neurol 2005;57:27–33.CrossRefGoogle ScholarPubMed
20.Hernán, MA, Logroscino, G, Rodríguez, LA.A prospective study of alcoholism and the risk of Parkinson's disease. J Neurol 2004;251(Suppl. 7):vII14–17.CrossRefGoogle ScholarPubMed
21.Gale, C, Martyn, C. Tobacco, coffee, and Parkinson's disease (Editorials). BMJ 2003;326:561–562.Google Scholar
22.Hellenbrand, W, Seidler, A, Robra, BP et al. Smoking and Parkinson's disease: a case-control study in Germany. Int J Epidemiol 1997;26:328–329.CrossRefGoogle ScholarPubMed
23.Rybicki, BA, Johnson, CC, Peterson, EL et al. A family history of Parkinson's disease and its effect on other PD risk factors. Neuroepidemiology 1999;18:270–278.CrossRefGoogle ScholarPubMed
24.Scott, WK, Zhang, F, Stajich, JM et al. Family-based case-control study of cigarette smoking and Parkinson disease. Neurology 2005;64:442–447.CrossRefGoogle ScholarPubMed
25.Tanner, CM, Goldman, SM, Aston, DA et al. Smoking and Parkinson's disease in twins. Neurology 2002;58:581–588.CrossRefGoogle ScholarPubMed
26.Elbaz, A, Manubens-Bertran, JM, Baldereschi, M et al. Parkinson's disease, smoking, and family history. EUROPARKINSON Study Group. J Neurol 2000;247: 793–798.CrossRefGoogle ScholarPubMed
27.Paulson, GW, Dadmehr, N.Is there a premorbid personality typical for Parkinson's disease? Neurology 1991;41(Suppl. 2):73–76.CrossRefGoogle Scholar
28.Menza, M.The personality associated with Parkinson's disease. Curr Psychiatry Rep 2000;2:421–426.CrossRefGoogle ScholarPubMed
29.Fowler, JS, Volkow, ND, Wang, GJ et al. Inhibition of monoamine oxidase B in the brains of smokers. Nature 1996;379:733–736.CrossRefGoogle ScholarPubMed
30.Castagnoli, KP, Steyn, SJ, Petzer, JP, Van der Schyf, CJ, Castagnoli, N Jr.Neuroprotection in the MPTP Parkinsonian C57BL/6 mouse model by a compound isolated from tobacco. Chem Res Toxicol 2001;14:523–527.CrossRefGoogle ScholarPubMed
31.Schwarzschild, MA, Xu, K, Oztas, E et al. Neuroprotection by caffeine and more specific A2A receptor antagonists in animal models of Parkinson's disease. Neurology 2003;61:S55–S61.CrossRefGoogle ScholarPubMed