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Quality of life and subthreshold obsessive-compulsive disorder

Published online by Cambridge University Press:  24 June 2014

Arianna Goracci ,
Mirko Martinucci ,
Anastassia Kaperoni ,
Andrea Fagiolini ,
Chiara Sbaragli ,
Eleonora Corsi  and
Paolo Castrogiovanni
Arianna Goracci*
Affiliation:
Department of Neuroscience, Psychiatry Division, University of Siena School of Medicine, Siena, Italy
Mirko Martinucci
Affiliation:
Department of Neuroscience, Psychiatry Division, University of Siena School of Medicine, Siena, Italy
Anastassia Kaperoni
Affiliation:
Department of Neuroscience, Psychiatry Division, University of Siena School of Medicine, Siena, Italy
Andrea Fagiolini
Affiliation:
Department of Neuroscience, Psychiatry Division, University of Siena School of Medicine, Siena, Italy Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA, USA
Chiara Sbaragli
Affiliation:
Department of Neuroscience, Psychiatry Division, University of Siena School of Medicine, Siena, Italy
Eleonora Corsi
Affiliation:
Department of Neuroscience, Psychiatry Division, University of Siena School of Medicine, Siena, Italy
Paolo Castrogiovanni
Affiliation:
Department of Neuroscience, Psychiatry Division, University of Siena School of Medicine, Siena, Italy
*
Dr Arianna Goracci, Department of Neuroscience, Psychiatry Division, University of Siena School of Medicine, Viale Bracci 1, 53100 Siena, Italy. Tel: +39-0577-586275; Fax: +39-0577-233451; E-mail: [email protected]
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Abstract

Objective:

This study investigates the relationship between subthreshold obsessive-compulsive disorder (OCD) and quality of life (QoL) in a sample from the Italian general population.

Methods:

A sample of 202 psychiatrically healthy (defined as absence of current axis I and axis II disorders) subjects was recruited by word of mouth from the residential population in the Siena, Salerno and Milano municipalities (Italy). All study subjects completed the Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q) and the Questionnaire for Obsessive-Compulsive Spectrum (OBS-SR), which explore a wide array of threshold and subthreshold OCD symptoms, behaviours and traits. A diagnostic assessment was conducted to exclude the presence of DSM-IV axis I and axis II disorders using the Mini International Neuropsychiatric Interview and the Structured Clinical Interview for DSM-III-R personality disorders, respectively.

Results:

A statistically significant correlation was found between the OBS-SR total score and the Q-LES-Q domains of physical health, subjective feelings, work, school, social relationships and general activities. There was also a statistically significant correlation between several Q-LES-Q and OBS-SR domains.

Conclusions:

The presence of subthreshold OCD is correlated with poorer QoL. More research is needed to evaluate if specific therapeutic interventions targeting subthreshold obsessive-compulsive symptoms can lead to a significant improvement in the QoL of the affected individuals.

Keywords

compulsiveobsessivequality of lifespectrumsubclinicalsubthreshold
Type
Research Article
Information
Acta Neuropsychiatrica , Volume 19 , Issue 6 , December 2007 , pp. 357 - 361
Copyright
Copyright © 2007 Blackwell Munksgaard

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References

Welkowitz, LA, Struening, EL, Pittman, J, Guardino, M, Welkowitz, J. Obsessive-compulsive disorder and comorbid anxiety problems in a national screening sample. J Anxiety Disord 2000;14:471–482. CrossRefGoogle Scholar
Bobes, J, Gonzales, MP, Bascaran, MT, Arango, C, Saiz, PA, Bousono, M. Quality of life and disability in patients with obsessive-compulsive disorder. Eur Psychiatry 2001;16:239–245. CrossRefGoogle ScholarPubMed
Masellis, M, Rector, NA, Richer, MA. Quality of life in OCD: differential impact of obsessions, compulsions, and depression comorbidity. Can J Psychiatry 2003;48:72–77. CrossRefGoogle ScholarPubMed
Koran, LM, Thienemann, ML, Devenport, R. Quality of life for patients with obsessive-compulsive disorder. Am J Psychiatry 1996;153:783–788. Google ScholarPubMed
Grabe, HJ, Meyer, C, Happke, Uet al. Prevalence, quality of life and psychosocial function in obsessive-compulsive disorder and subthreshold obsessive-compulsive disorder in Northern Germany. Eur Arch Psychiatry Clin Neurosci 2000;250:262–268. CrossRefGoogle Scholar
Bebbington, PE, Hurry, J, Tennant, C, Sturt, E, Wing, JK. Epidemiology of mental disorders in Camberwell. Psychol Med 1981;2:561–579. CrossRefGoogle Scholar
Bebbington, PE. Epidemiology of obsessive-compulsive disorder. Br J Psychiatry 1998;35:2–6. Google Scholar
Angst, J. Comorbidity of anxiety, phobia, compulsion and depression. Int Clin Psychopharmacol 1993;8:21–25. CrossRefGoogle ScholarPubMed
Dell’Osso, L, Cassano, GB, Sarno, Net al. Validity and reliability of the Structured Clinical Interview for Obsessive-Compulsive Spectrum (SCI-OBS) and of the Structured Clinical Interview for Social Phobia Spectrum (SCI-SHY). Int J Methods Psychiatr Res 2000;9:11–24. CrossRefGoogle Scholar
Dell’Osso, L, Rucci, P, Cassano, GBet al. Measuring social anxiety and obsessive-compulsive spectra: comparison of interviews and self-report instruments. Compr Psychiatry 2002;43:81–87. CrossRefGoogle ScholarPubMed
Frank, E, Shear, MK, Rucci, Pet al. Influence of panic-agoraphobic spectrum symptomatology on treatment response in patients with recurrent major depression. Am J Psychiatry 2000;157:1101–1107. CrossRefGoogle Scholar
Frank, E, Cyranowski, JM, Rucci, Pet al. Clinical significance of lifetime panic spectrum symptoms in the treatment of patients with bipolar I disorder. Arch Gen Psychiatry 2002;59:905–911. CrossRefGoogle ScholarPubMed
Dell’Osso, L, Rucci, P, Ducci, Fet al. Social anxiety spectrum. Eur Arch Psychiatry Clin Neurosci 2003;253:286–291. CrossRefGoogle ScholarPubMed
Rucci, P, Maser, JD. Instrument development in the Italy-USA Collaborative Spectrum Project. Epidemiol Psichiatr Soc 2000;9:249–256. CrossRefGoogle ScholarPubMed
Endicott, J, Nee, J, Harrison, W, Blumenthal, R. Quality of Life Enjoyment and Satisfaction Questionnaire: a new measure. Psychopharmacol Bull 1993;29:321–326. Google ScholarPubMed
Rossi, A, Rucci, P, Mauri, M, Maina, G, Pieraccini, F, Pallanti, S. Endicott J (For the EQUIP group). Validity and reliability of the Italian version of the quality of life, enjoyment and satisfaction questionnaire. Qual Life Res 2005;14:2323–2328. CrossRefGoogle Scholar
Sheehan, DV, Lecrubier, Y, Sheehan, KHet al. Mini International Neuropsychiatric Interview (M.I.N.I.). Tampa, Florida: University of South Florida Institute for Research in Psychiatry and Paris, France: INSERM – Hopital de la Salpétrière, 1994. Google Scholar
Spitzer, RL, Williams, JBW, Gibbon, Met al. Structured Clinical Interview for DSM-III-R – Personality Disorders (SCID-II, Version 1.0). Washington, DC: American Psychiatric Press, 1990. Google Scholar
Zucker, BG, Craske, MG, Blackmore, MA, Nitz, A. Cognitive behavioral workshop for subclinical obsessions and compulsions. Behav Res Ther 2006;44:289–304. CrossRefGoogle ScholarPubMed
Green, MJ, Malhi, GS. Neural mechanisms of the cognitive control of emotion. Acta Neuropsychiatr 2006;18:144–153. CrossRefGoogle ScholarPubMed