Hostname: page-component-78c5997874-mlc7c Total loading time: 0 Render date: 2024-11-16T17:07:51.124Z Has data issue: false hasContentIssue false
  • English
  • Français

Neuropsychological profile of a male psychiatric patient with a Morgagni-Stewart-Morel syndrome

Published online by Cambridge University Press:  10 November 2014

Aksel Hansen ,
Liliana Engelhardt ,
Wolfgang Pleschutznig ,
Gerhard Dammann  and
Stephanie Vietze
Aksel Hansen*
Affiliation:
Department of Psychiatry, Psychiatrische Dienste Thurgau, Switzerland
Liliana Engelhardt
Affiliation:
Department of Psychiatry, Psychiatrische Dienste Thurgau, Switzerland
Wolfgang Pleschutznig
Affiliation:
Department of Psychiatry, Psychiatrische Dienste Thurgau, Switzerland
Gerhard Dammann
Affiliation:
Department of Psychiatry, Psychiatrische Dienste Thurgau, Switzerland
Stephanie Vietze
Affiliation:
Department of Psychiatry, Psychiatrische Dienste Thurgau, Switzerland
*
Aksel Hansen, Psychiatrische Dienste Thurgau, Seeblickstrasse 3, Postfach 154 8596, Münsterlingen, Switzerland. Tel: 0041716864032;Fax: 0041716864035; E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

In 1765 Giovanni Morgagni described a syndrome consisting of hyperostosis frontalis interna (HFI), obesity and hirsutism. In 1928 Stewart and in 1930 Morel added neuropsychiatric symptoms, e.g. depression and dementia, which led to the definition of the Morgagni-Stewart-Morel Syndrome (MSM). Although mostly women were characterized in literature no gender specifity is demanded. This case report presents the rare case of a 66 year old male psychiatric patient with Morgagni-Stewart-Morel Syndrome. The patient complained of loss of concentration and difficulties with activities of daily living. Admission diagnosis was an opioid misuse on the basis of a chronic pain syndrome. In this case report we are describing clinical features, the patient history and technical (MRI) and neuropsychological tests. Although severe psychiatric symptoms and neuropsychological deficits are commonly seen in these patients, our patient showed only mild symptoms. This case reports shows the possibility of a male patient with MSM. If MSM is a separate entity or just an epiphenomena of hormone dysregulation should be investigated in further studies.

Keywords

hyperostosis frontalis internahormone dysregulationMorgagni-Stewart-Morel syndromeneuropsychological testing
Type
Case Report
Information
Acta Neuropsychiatrica , Volume 27 , Issue 1 , February 2015 , pp. 60 - 64
Check for updates
Copyright
© Scandinavian College of Neuropsychopharmacology 2014 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Morgagni, GB. Adversaria Anatomica. Padua: Francis A. Coutway Library of Medicine, 1719/1984.Google Scholar
2.Antón, SC. Endocranial hyperostosis in Sangiran 2, Gibraltar 1, and Shanidar 5. Am J Phys Anthropol 1997;102:111–122.Google Scholar
3.Hershkovitz, I, Greenwald, C, Rothschild, BMet al. Hyperostosis frontalis interna: an anthropological perspective. Am J Phys Anthropol 1999;109:303–325.Google Scholar
4.She, R, Szakacs, J. Hyperostosis frontalis interna: case report and review of literature. Ann Clin Lab Sci 2004;34:206–208.Google Scholar
5.Rühli, FJ, Henneberg, M. Are hyperostosis frontalis interna and leptin linked? A hypothetical approach about hormonal influence on human microevolution. Med Hypotheses 2002;58:378–381.CrossRefGoogle ScholarPubMed
6.De Zubicaray, GI, Chalk, JB, Rose, SE, Semple, J, Smith, GA. Deficits on self ordered tasks associated with hyperostosis frontalis interna. J Neurol Neurosurg Psychiatry 1997;63:309–314.Google Scholar
7.Stewart, RM. Localized cranial hyperostosis in the insane. J Neurol Psychopathol 1928;8:321–331.CrossRefGoogle ScholarPubMed
8.Morel, F. L’hyperostose Frontale Interne. Geneva: Chapalay and Mottier, 1929.Google Scholar
9.De Zubicaray, GI, Chalk, JB, Rose, SE, Semple, J, Smith, GA. Deficits on selfordered tasks associated with hyperostosis frontalis interna. J Neurol Neurosurg Psychiatr 1997;63:309–314.Google Scholar
10.Henschen, F. Morgagni’s syndrome. Virchows Arch A Pathol Anat Histol 1976;370:1–11.CrossRefGoogle ScholarPubMed
11.Wålinder, J. Hyperostosis frontalis interna and mental morbidity. Br J Psychiatry 1977;131:155–159.CrossRefGoogle ScholarPubMed
12.Koller, MF, Papassotiropoulos, A, Henke, Ket al. Evidence of a genetic basis of Morgagni-Stewart-Morel syndrome. A case report of identical twins. Neurodegener Dis 2005;2:56–60.CrossRefGoogle ScholarPubMed
13.Klein, D, Rosatti, P, Mach, RS, Ferrier, PE, Rauch, S. Morgagni-Morel syndrome an independent clinical and genetic entity, demonstrated in a family study covering 4 generations. Schweiz Arch Neurol Neurochir Psychiatr 1973;112:239–250.Google Scholar
14.Franke, GH. SCL-90-R. Die Symptom-Checkliste von L. R. Derogatis – Deutsche Version – Manual, 2, vollständige überarbeitete und neu normierte Auflage. Göttingen: Beltz Test GMBH, 2002.Google Scholar
15.Aebi, C. Validierung der neuropsychologischen Testbatterie CERAD-NP: eine Multi-Center Studie. Dissertation, Universität Basel, Philosophisch-Historische Fakultät Universität Basel, 2002.Google Scholar
16.Thurstone, LL. Primary mental abilities. Chicago: University of Chicago Press, 1938.Google Scholar
17.Army Individual Test Battery. Manual of directions and scoring. Washington, DC: War Department, Adjutant General’s Office, 1944.Google Scholar