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Impulsivity in adolescent bipolar disorder

Published online by Cambridge University Press:  24 June 2014

Kirsten E. Gilbert ,
Jessica H. Kalmar ,
Fay Y. Womer ,
Philip J. Markovich ,
Brian Pittman ,
Susan Nolen-Hoeksema  and
Hilary P. Blumberg
Kirsten E. Gilbert
Affiliation:
Department of Psychology, Yale University, New Haven, Connecticut, USA
Jessica H. Kalmar
Affiliation:
Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA
Fay Y. Womer
Affiliation:
Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA
Philip J. Markovich
Affiliation:
Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA
Brian Pittman
Affiliation:
Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA
Susan Nolen-Hoeksema
Affiliation:
Department of Psychology, Yale University, New Haven, Connecticut, USA
Hilary P. Blumberg
Affiliation:
Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA Child Study Center, Yale School of Medicine, New Haven, Connecticut, USA
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Extract

Objective: Increased impulsivity has been shown to be a trait feature of adults with bipolar disorder (BD), yet impulsivity has received little study in adolescents with BD. Thus, it is unknown whether it is a trait feature that is present early in the course of the disorder. We tested the hypotheses that self-reported impulsiveness is increased in adolescents with BD, and that it is present during euthymia, supporting impulsiveness as an early trait feature of the disorder.

Methods: Impulsiveness was assessed in 23 adolescents with BD and 23 healthy comparison (HC) adolescents using the self-report measure of impulsivity, the Barratt Impulsiveness Scale (BIS), comprised by attentional, motor and non-planning subscale scores. Effects of subscale scores and associations of scores with mood state and course features were explored.

Results: Total and subscale BIS scores were significantly higher in adolescents with BD than HC adolescents. Total, attentional and motor subscale BIS scores were also significantly higher in the subset of adolescents with BD who were euthymic, compared to HC adolescents. Adolescents with BD with rapid-cycling and chronic mood symptoms had significantly higher total and motor subscale BIS scores than adolescents with BD without these course features.

Conclusion: These results suggest increased self-reported impulsiveness is a trait feature of adolescents with BD. Elevated impulsivity may be especially prominent in adolescents with rapid-cycling and chronic symptoms.

Keywords

adolescentsbipolar disorderimpulsivity
Type
Research Article
Information
Acta Neuropsychiatrica , Volume 23 , Issue 2 , April 2011 , pp. 57 - 61
Copyright
Copyright © Cambridge University Press 2011

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References

1.Moeller, FG, Barratt, ES, Dougherty, DM, Schmitz, JM, Swann, AC.Psychiatric aspects of impulsivity. Am J Psychiatry 2001;158:1783–1793.CrossRefGoogle ScholarPubMed
2.Swann, AC, Anderson, JC, Dougherty, DM, Moeller, FG.Measurement of the inter-episode impulsivity in bipolar disorder. Psychiatry Res 2001;101:195–197.CrossRefGoogle ScholarPubMed
3.Swann, AC, Pazzaglia, PJ, Nicholls, A, Dougherty, DM, Moeller, FG.Impulsivity and phase of illness in bipolar disorder. J Affect Disord 2003;73:105–111.CrossRefGoogle ScholarPubMed
4.Harmon-Jones, E, Barratt, ES, Wigg, C.Impulsiveness, aggression, reading, and the P300 of the event-related potential. Pers Individ Dif 1997;22:439–445.CrossRefGoogle Scholar
5.Corruble, E, Benyamina, A, Bayle, F, Falissard, B, Hardy, P.Understanding impulsivity in severe depression? A psychometrical contribution. Prog Neuropsychopharmacol Biol Psychiatry 2003;27:829–833.CrossRefGoogle ScholarPubMed
6.Barratt, ES, Patton, JH. Impulsivity: cognitive, behavioral, and psychophysiological correlates. In: Zuckerman, M, ed. Biological basis of sensation-seeking, impulsivity, and anxiety. Englewood Cliffs: Lawrence Erlbaum Associates, 1983: 77–116.Google Scholar
7.Swann, AC, Moeller, FG, Steinberg, JL, Schneider, L, Barratt, ES, Dougherty, DM.Manic symptoms and impulsivity during bipolar depressive episodes. Bipolar Disord 2007;9:206–212.CrossRefGoogle ScholarPubMed
8.Swann, AC, Steinberg, JL, Lijffijt, F, Moeller, FG.Impulsivity: differential relationship to depression and mania in bipolar disorder. J Affect Disord 2008;206: 241–248.CrossRefGoogle Scholar
9.Peluso, MAM, Hatch, JP, Glahn, DC et al. Trait impulsivity in patients with mood disorders. J Affect Disord 2007;100:227–231.CrossRefGoogle ScholarPubMed
10.Holmes, MK, Bearden, CE, Barguil, M et al. Conceptualizing impulsivity and risk taking in bipolar disorder: importance of history of alcohol abuse. Bipolar Disord 2009;11:33–40.CrossRefGoogle Scholar
11.Swann, AC, Dougherty, DM, Pazzaglia, PJ, Pham, M, Steinberg, JL, Moeller, FG.Increased impulsivity associated with severity of suicide attempt history in patients with bipolar disorder. Am J Psychiatry 2005;162:1680–1687.CrossRefGoogle ScholarPubMed
12.Swann, AC, Lijffijt, M, Lane, SD, Steinberg, JL, Moeller, FG.Increased trait-like impulsivity and course of illness in bipolar disorder. Bipolar Disord 2009;11:280–288.CrossRefGoogle ScholarPubMed
13.Dickstein, DP, Treland, JE, Snow, J et al. Neuropsychological performance in pediatric bipolar disorder. Biol Psychiatry 2004;55:32–39.CrossRefGoogle ScholarPubMed
14.Dickstein, DP, Nelson, EE, McClure, EB et al. Cognitive flexibility in phenotypes of pediatric bipolar disorder. J Am Acad Child Adolesc Psychiatry 2007;46:341–355.CrossRefGoogle ScholarPubMed
15.Gorrindo, T, Blair, RJ, Budhani, S, Dickstein, DP, Pine, DS, Leibenluft, E.Deficits on a probabilistic response-reversal task in patients with pediatric bipolar disorder. Am J Psychiatry 2005;162:1975–1977.CrossRefGoogle ScholarPubMed
16.McClure, EB, Treland, JE, Snow, J et al. Deficits in social cognition and response flexibility in pediatric bipolar disorder. Am J Psychiatry 2005;162:1644–1651.CrossRefGoogle ScholarPubMed
17.Kaufman, J, Birmaher, B, Brent, D et al. Schedule for affective disorders and schizophrenia for school-age children-present and lifetime version (K-SADS-PL): initial reliability and validity data. J Am Acad Child Adolesc Psychiatry 1997;36:980–988.CrossRefGoogle ScholarPubMed
18American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 4th edn (text revision). Washington DC: American Psychiatric Association, 2000.Google Scholar
19.Lish, JD, Weissman, MM, Adams, PB, Hoven, CW, Bird, H.Family psychiatric screening instruments for epidemiologic studies: pilot testing and validation. Psychiatry Res 1995;57:169–180.CrossRefGoogle ScholarPubMed
20.Emslie, GJ, Weinberg, WA, Rush, AJ, Adams, RM, Rintelmann, JW.Depressive symptoms by self-report in adolescents: phase I of the development of a questionnaire for depression by self-report. J Child Neurol 1990;5:449–453.CrossRefGoogle ScholarPubMed
21.Young, RC, Biggs, JT, Ziegler, VE, Meyer, DA.A rating scale for mania: reliability, validity and sensitivity. Br J Psychiatry 1978;133:429–435.CrossRefGoogle ScholarPubMed
22.Barratt, ES. Impulsiveness and aggression. In: Monahan, J, Steadman, HJ, eds. Violence and mental disorder: developments in risk assessment. Chicago: University of Chicago, 1994: 61–79.Google Scholar
23.Patton, JH, Stanford, MS, Barratt, ES.Factor structure of the Barratt Impulsiveness Scale. J Clin Psychol 1995;51:768–774.3.0.CO;2-1>CrossRefGoogle ScholarPubMed
24.Blumberg, HP, Hoi-Chung, L, Skudlarski, P et al. A functional magnetic resonance imaging study of bipolar disorder; state- and trait-related dysfunction in ventral prefrontal cortices. Arch Gen Psychiatry 2003;60:601–609.CrossRefGoogle ScholarPubMed
25.Blumberg, HP, Krystal, JH, Bansal, R et al. Age, rapid-cycling, and pharmacotherapy effects on ventral prefrontal cortex in bipolar disorder: a cross-sectional study. Biol Psychiatry 2006;59:611–618.CrossRefGoogle ScholarPubMed
26.Blumberg, HP, Martin, A, Kaufman, J et al. Frontostriatal abnormalities in adolescents with bipolar disorder: preliminary observations from functional MRI. Am J Psychiatry 2003;160:1345–1347.CrossRefGoogle ScholarPubMed
27.Kalmar, JH, Wang, F, Chepenik, LG et al. Relation between amygdala structure and function in adolescents with bipolar disorder. J Am Acad Child Adolesc Psychiatry 2009;48:636–642.CrossRefGoogle ScholarPubMed
28.Leibenluft, E, Rich, BA, Vinton, DT et al. Neural circuitry engaged during unsuccessful motor inhibition in pediatric bipolar disorder. Am J Psychiatry 2007;164:152–160.CrossRefGoogle ScholarPubMed
29.Malloy-Diniz, L, Fuentes, D, Leite, WB, Correa, H, Bechara, A.Impulsive behavior in adults with attention deficit/hyperactivity disorder: characterization of attentional, motor, and cognitive impulsiveness. J Int Neuropsychol Soc 2007;13:693–698.CrossRefGoogle ScholarPubMed