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Heroin-dependent patients attempting and not attempting suicide: a comparison

Published online by Cambridge University Press:  24 June 2014

Ayhan Kalyoncu ,
Hasan Mırsal ,
Özkan Pektaş ,
Devran Tan  and
Mansur Beyazyürek
Ayhan Kalyoncu*
Affiliation:
Department of Psychiatry, Faculty of Medicine, Maltepe University, Istanbul, Turkey
Hasan Mırsal
Affiliation:
Department of Psychiatry, Faculty of Medicine, Maltepe University, Istanbul, Turkey
Özkan Pektaş
Affiliation:
Department of Psychiatry, Faculty of Medicine, Maltepe University, Istanbul, Turkey
Devran Tan
Affiliation:
Department of Psychiatry, Faculty of Medicine, Maltepe University, Istanbul, Turkey
Mansur Beyazyürek
Affiliation:
Department of Psychiatry, Faculty of Medicine, Maltepe University, Istanbul, Turkey
*
Ayhan Kalyoncu, MD, Balıklı Rum Hastanesi Vakfı, Anatolia Klinikleri, BelgradKapı Yolu No:2 Zeytinburnu, Istanbul, Turkey. Tel: +90 212 5471600; Fax: +90 212 5102075; E-mail: [email protected]
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Abstract

Objective:

Heroin dependence is a serious illness associated with an increased risk of suicidal behaviour. There are many risk factors associated with heroin dependence. The current study examined the sociodemographic and clinical characteristics of a number of young adult heroin-dependent patients who had attempted suicide.

Methods:

We studied a group of 108 young adult heroin-dependent patients in our in-patient clinics. All diagnoses were made according to DSM-IV diagnostic criteria using the Structured Clinical Interview for DSM-IV Axis I-II Disorders (SCID-I, II). The age range of patients was 18–24 years. Their substance abuse histories were assessed by semistructured interview. The Addiction Severity Index (ASI) was administered to all the patients. Serum total cholesterol and high-density lipoprotein cholesterol (HDL-C) levels were routinely measured. In the statistical analyses, Student’s t test, and chi-squared tests were applied.

Results:

Of the 108 heroin-dependent patients, 40 (37.0%) had histories of attempted suicide. There was a statistically significant difference in the age at which heroin use had commenced between female attempters [mean = 16.82, standard deviation (SD) = 3.06] and nonattempters (mean = 18.32, SD = 2.68, t= 2.25, P < 0.05). Both the male (mean = 33.35, SD = 4.05) and the female (mean = 28.00, SD = 5.36) attempters had significantly higher ASI scores than did the male (mean = 20.16, SD = 3.80) and the female (mean = 18.88, SD = 4.14) nonattempters (t= 14.34, P < 0.001; t= 5.25, P < 0.001, respectively). A significant difference in total cholesterol (mean = 131.8, SD = 19.3; mean = 172.2, SD = 21.3, t= 3.9, P < 0.05) and HDL-C (mean = 30.9, SD = 1.0 and mean = 54.8, SD = 13.7; t= 5.1, P < 0.05) levels between the group of violent and nonviolent suicide attempters was revealed.

Conclusions:

These results suggest that suicide attempts in young adult heroin-dependent patients are associated with more profound biopsychosocial pathology and decreased serum cholesterol levels. In particular, low levels of total cholesterol and HDL-C might indeed be associated with violent suicide attempts in young heroin-dependent patients.

Keywords

characteristicscholesterolheroin dependencesuicide
Type
Research Article
Information
Acta Neuropsychiatrica , Volume 19 , Issue 5 , October 2007 , pp. 297 - 303
Copyright
Copyright © 2007 Blackwell Munksgaard

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