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Dystonie reactions and hallucinations: a rare adverse-effect?

Published online by Cambridge University Press:  18 September 2015

L.H.W.M. Kaiser  and
M.P.J. Schols
L.H.W.M. Kaiser*
Affiliation:
APZ ‘Wolfheze’
M.P.J. Schols
Affiliation:
APZ ‘Wolfheze’
*
APZ ‘Wolfheze’ Wolfhezerweg 2 6874 BE Wolfheze
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Summary

Dystonie reactions and hallucinations: a rare adverse-effect? One of the intriguing side-effects of neuroleptics is the acute dystonie reaction like oculogyric crises. It is seldom mentioned that the dystonie reaction may be combined with hallucinations. This combination of acute dystonia with hallucinations may be explained by overstimulation of dopamine-receptors in the striatal neurons. Awareness of these hallucinations as a complication of neuroleptics is essential to prevent that neuroleptic dose will be increased; instead it must be lowered. Prevention of the dystonia is critical. These side effects may be suppressed with anti-parkinsonian drugs. Information to the patient in due time may prevent anxiety about the side effects.

Keywords

dystoniahallucinationsdopaminedystoniehallucinatiesdopamine
Type
Research Article
Information
Acta Neuropsychiatrica , Volume 4 , Issue 1 , March 1992 , pp. 12 - 16
Copyright
Copyright © Scandinavian College of Neuropsychopharmacology 1992

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References

Literatuur

1.Hermesh, H, Shalev, A, Munitz, H.Contribution of adverse drug reaction to admission rates in an acute psychiatric ward. Acta psychiat scand 1985; 72: 104–10.CrossRefGoogle Scholar
2.Stewart, RB, Springer, PK, Adams, JE.Drug-related admissions to an inpatient psychiatric unit. Am J Psychiat 1980; 137: 1093–95.Google Scholar
3.Wolf, B, Grohmann, R, Schmidt, LG, Ruther, E.Psychiatric admissions due to adverse drug reactions. Compreh Psychiat 1989; 30: 534–45.CrossRefGoogle ScholarPubMed
4.Johnson, DAW.Drug-induced psychiatric disorders. Drugs 1981;22:57–69.CrossRefGoogle ScholarPubMed
5.Simpson, GM, Varga, E, Haher, EJ.Psychotic exacerbations produced by neuroleptics. Dis nerv Syst 1976; 37: 367–69.Google ScholarPubMed
6.Chiu, LPW.Transient recurrence of auditory hallucinations during acute dystonia. Br J Psychiat 1989; 155: 110–13.CrossRefGoogle ScholarPubMed
7.Rupniak, NMJ, Jenner, P, Marsden, CDAcute dystonia induced by neuroleptic drugs. Psychopharmacol 1986; 88: 403–19.CrossRefGoogle ScholarPubMed
8.Carlsson, A.The current status of the dopamine hypothesis of schizophrenia. Neuropsychopharmacol 1988; 1: 179–86.CrossRefGoogle ScholarPubMed
9.Boer den, JA, Westenberg, HGM, Verhoeven, WMA. Atypische neuroleptika bij de behandeling van schizofrene psychosen. COBO-bulletin 1990; 1: 10–7.Google Scholar