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  3. Dormancy and Low Growth States in Microbial Disease
  • Cited by 11
Publisher:
Cambridge University Press
Online publication date:
August 2009
Print publication year:
2003
Online ISBN:
9780511546242
DOI:
https://doi.org/10.1017/CBO9780511546242
Subjects:
Life Sciences, Pathology and Laboratory Science, Microbiology and Immunology, Infectious Disease, Medicine
Series:
Advances in Molecular and Cellular Microbiology (3)
Information

Book description

All cellular life-forms can exist in replicating and non-replicating states. Organisms replicate only when the conditions are beneficial, and when not replicating they concentrate on survival of these environmental stresses. Many bacteria, harmful to humans, survive the period of infection in a low growth state. This 2003 book addresses the basic science of microbial dormancy and low growth states, putting this in the context of human medicine. Such fundamental topics as bacterial growth and non-growth, culturability and viability are covered, as well as survival of the host's immune response, and inter-bacterial signalling. Following this introduction, more medically focused topics are discussed, namely antibiotic resistance arising during stationary phase, biofilms, the bacteria which cause gastric ulcers and tuberculosis as the classic persistent bacterial infection. This book will interest graduate students and researchers in medical microbiology, immunology and infectious disease medicine who are interested in bacterial dormancy in relation to disease.

Reviews

Review of the hardback:'… an excellent addition to the literature …'Microbiology Today

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