Diseases of the Nervous System: Clinical Neuroscience and Therapeutic Principles

doi:10.1017/CBO9781316134993

Diseases of the Nervous System

Clinical Neuroscience and Therapeutic Principles

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Bartsch, T. Knight, Y. E. and Goadsby, P. J. 2004. Activation of 5‐HT1B/1D receptor in the periaqueductal gray inhibits nociception. Annals of Neurology, Vol. 56, Issue. 3, p. 371.

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Lin, L. and Adey, C. 2007. Presentation of Hemiplegic Migraine—Hemiplegia and Hemi-Sensory Loss following General Anaesthesia. Anaesthesia and Intensive Care, Vol. 35, Issue. 3, p. 418.

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3rd edition
Edited by Arthur K. Asbury, University of Pennsylvania School of Medicine, Guy M. McKhann, The Johns Hopkins University School of Medicine, W. Ian McDonald, University College London, Peter J. Goadsby, University College London, Justin C. McArthur, The Johns Hopkins University School of Medicine

Publisher:: Cambridge University Press
Online publication date:: August 2016
Print publication year:: 2002
Online ISBN:: 9781316134993
DOI:: https://doi.org/10.1017/CBO9781316134993

Subjects:: Neurology and Clinical Neuroscience, Medicine

463.00 (GBP)

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The third edition of a neurology classic, this two-volume text is the most comprehensive neurology reference available. It encompasses the basic neuroscience and clinical features of the full range of neurological disorders, written by leading international experts in the field. Disease mechanisms are reviewed comprehensively, with particular relevance to the principles of therapy. Sections cover the general principles of neurological disease, disorders of higher function, motor control, special senses, spine and spinal cord, bodily function, headache and pain, neuromuscular disorders, epilepsy, cerebrovascular disorders, neoplastic disorders, autoimmune disorders, disorders of myelin, infections, trauma and toxic disorders, degenerative disorders, and neurological manifestations of systemic conditions. Each section, under the direction of one of the distinguished editors, is a text-within-a-text, offering the most reliable account of its topic currently available. Current, comprehensive and authoritative, this is the definitive reference for neurologists, neurosurgeons, neuropsychiatrists, indeed everyone with a professional or research interest in the neurosciences.

‘… a remarkable and successful effort to present in a comprehensive yet concise manner a massive amount of data on neurological diseases … the main value of this book for psychiatrists or neurologists working with children resides in the superb coverage of the general pathophysiological and therapeutic aspects. Paediatric specialists will find in this book new concepts and ideas about neurological disorders that may be of value at any age, allowing a better and more up-to-date understanding of some of the conditions they have to deal with.’

Source: European Child & Adolescent Psychiatry

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Contents

Frontmatter
pp i-iv
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Dedication
pp v-vi
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Contents
pp vii-xii
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List of contributors
pp xiii-xxxii
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Editor's preface
pp xxxiii-xxxiv
- By Arthur K. Asbury, University of Pennsylvania School of Medicine, Philadelphia, PA, USA, Guy M. McKhann, The Zanvyl Krieger Mind & Brain Institute Johns Hopkins University, W. Ian McDonald, Institute of Neurology, University College London, Royal College of Physicians, London, UK, Peter J. Goadsby, Institute of Neurology, The National Hospital for Neurology and Neurosurgery, London, UK, Justin C. McArthur, Departments of Neurology and Epidemiology, Johns Hopkins University Baltimore, MD, USA
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PART I - INTRODUCTION AND GENERAL PRINCIPLES
pp 1-2
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1 - Pathophysiology of nervous system diseases
pp 3-13
- By Justin C. McArthur, Departments of Neurology and Epidemiology, Johns Hopkins University Baltimore, MD, USA, Guy M. McKhann, The Zanvyl Krieger Mind and Brain Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA, W. Ian McDonald, Institute of Neurology, University College London, Royal College of Physicians, London, UK, Peter J. Goadsby, Institute of Neurology, The National Hospital for Neurology and Neurosurgery, London, UK, Arthur K. Asbury, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
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2 - Genetics of common neurological disorders
pp 14-31
- By Orest Hurko, Department of Investigational Medicine GlaxoSmithKline Pharmaceuticals
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3 - Repeat expansion and neurological disease
pp 32-54
- By J. Paul Taylor, Neurogenetics Branch National Institute of Neurological Disorders and Stroke, Andrew P. Lieberman, Neurogenetics Branch National Institute of Neurological Disorders and Stroke, Kenneth H. Fischbeck, Neurogenetics Branch National Institute of Neurological Disorders and Stroke
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4 - Cell birth and cell death in the central nervous system
pp 55-61
- By Samuel J. Pleasure, Department of Neurology University of California, San Francisco, David E. Pleasure, Departments of Neurology and Pediatrics Children's Hospital of Philadelphia
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5 - Neuroprotection in cerebral ischemia
pp 62-78
- By Jin-Moo Lee, Washington University School of Medicine, Dennis W. Choi, Department of Neurosciences Merck Research Laboratories
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6 - Promoting recovery of neurological function
pp 79-104
- By Ted Abel, Department of Biology University of Pennsylvania, Michael E. Selzer, Department of Neurology Hospital of the University of Pennsylvania
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7 - Measurement of neurological outcomes
pp 105-117
- By Jeremy Hobart, Department of Neurology The Peninsula Medical School Derriford Hospital Plymouth, Devon, UK, Alan J. Thompson, Neurological Outcome Measurement Unit Institute of Neurology Queen Square
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8 - Principles of clinical neuro-epidemiology
pp 118-126
- By Michael D. Hill, Department of Clinical Neurosciences, University of Calgary, Alberta, Canada, Thomas E. Feasby, Department of Clinical Neurosciences, University of Calgary, Alberta, Canada
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9 - Principles of therapeutics
pp 127-130
- By Peter J. Goadsby, Institute of Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK
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10 - Windows on the working brain: functional imaging
pp 131-145
- By John A. Detre, Department of Neurology, Paul D. Acton, Department of Radiology, University of Pennsylvania, PA, USA
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11 - Windows on the working brain: magnetic resonance spectroscopy
pp 146-159
- By James W. Prichard, Department of Neurology, Yale Medical School, New Haven, CT, USA, Jeffrey R. Alger, Department of Radiology, University of California at Los Angeles, CA, USA, Douglas Arnold, Department of Neurology, Montreal Neurological Institute, Canada, Ognen A.C. Petroff, Department of Neurology, Yale Medical School, New Haven, CT, USA, Douglas L. Rothman, Department of Diagnostic Radiology, Yale Medical School, New Haven, CT, USA
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12 - Windows on the working brain: evoked potentials, magnetencephalography and depth recording
pp 160-174
- By Hans-Joachim Freund, University of Dusseldorf Neurology Clinic, Germany, Hans J. Heinze, University of Magdeburg, Germany
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PART II - DISORDERS OF HIGHER FUNCTION
pp 175-176
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13 - Congenital disorders of cerebral cortical development
pp 177-194
- By Ganeshwaran H. Mochida, Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA, Christopher A. Walsh, Harvard Medical School, Boston, MA, USA
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14 - The aging brain: morphology, imaging and function
pp 195-209
- By Marilyn S. Albert, Department of Psychiatry and Neurology, Harvard Medical School, Boston, MA, USA, Guy M. McKhann, Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD, USA
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15 - Neurodegenerative diseases
pp 210-236
- By Stanley B. Prusiner, Institute for Neurodegenerative Diseases and Departments of Neurology
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16 - Aging and dementia: principles, evaluation and diagnosis
pp 237-251
- By Sudha Seshadri, Framingham Heart Study, Department of Neurology, Boston University School of Medicine, Framingham, MA, USA, David A. Drachman, Department of Neurology, University of Massachusetts Medical School, Worcester, MA, USA
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17 - Alzheimer's Disease
pp 252-266
- By Raymond J. Kelleher, Memory Disorders Unit, Neurology Service, Massachusetts General Hospital, and Department of Neurology, Harvard Medical School, Boston, MA, USA, John H. Growdon, Memory Disorders Unit, Neurology Service, Massachusetts General Hospital, and Department of Neurology, Harvard Medical School, Boston, MA, USA
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18 - Dementia with Lewy bodies
pp 267-282
- By Pamela J. McLean, Department of Neurology, Massachusetts General Hospital East, Charlestown, MA, USA, Estrella Gómez-Tortosa, Department of Neurology, Massachusetts General Hospital East, Charlestown, MA, USA, Michael C. Irizarry, Department of Neurology, Massachusetts General Hospital East, Charlestown, MA, USA, Bradley T. Hyman, Department of Neurology, Massachusetts General Hospital East, Charlestown, MA, USA
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19 - Frontotemporal dementia
pp 283-288
- By Bruce L. Miller, Department of Neurology, UCSF School of Medicine, San Francisco, CA, USA, Howard J. Rosen, Department of Neurology, UCSF School of Medicine, San Francisco, CA, USA, Michael Greicius, Department of Psychiatry and Behavioral Sciences, Stanford, CA, USA
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20 - Consciousness and its disorders
pp 289-300
- By Antonio R. Damasio, Department of Neurology, University of Iowa College of Medicine, Iowa City, IA, USA
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21 - Mechanisms of memory and amnestic syndromes
pp 301-316
- By John D.E. Gabrieli, Department of Psychology, Stanford University, Palo Alto, CA, USA, Silvia A. Bunge, Department of Psychology, Stanford University, Palo Alto, CA, USA
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22 - Acquired disorders of language
pp 317-330
- By John Hart, Laboratory of Cognition and Brain Imaging, Donald W. Reynolds Center on Aging, Unversity of Arkansas Medical School, USA, Ola A. Selnes, Department of Neurology, School of Medicine and Department of Cognitive Science, Krieger Mind/Brain Institute, The Johns Hopkins University, MD, USA
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23 - Neglect
pp 331-347
- By Kenneth M. Heilman, Department of Neurology, University of Florida College of Medicine, Gainesville, FL, USA
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Clinical Neuroscience and Therapeutic Principles

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