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  • Cited by 164
Publisher:
Cambridge University Press
Online publication date:
September 2009
Print publication year:
1996
Online ISBN:
9780511529764

Book description

Cytokinesis is the division of the cell body that follows the sorting and transport of chromosomes. This book traces the history of some of the major ideas in the field and gives an account of our current knowledge of animal cytokinesis. It contains descriptions of division in different kinds of cells and the proposed explanations of the mechanisms underlying the visible events. Experiments devised to test cell division theories are described and explained. The forces necessary for cytokinesis now appear to originate from the interaction of linear polymers and motor molecules that have roles in force production, motion and shape change that occur in other phases of the biology of the cell. The localization of the force-producing division mechanism to a restricted linear part of the subsurface is caused by the mitotic apparatus, the same cytoskeletal structure that ensures orderly mitosis.

Reviews

"Rappaport has been studying cleavage in marine embryos and tissue culture cells since the early 1960's... His book is clearly a labor of love: it includes a thorough review of more than 500 papers going back to the 1870s... Many of the pages are devoted to obsolete theories that will appeal to classical cytologists, science historians, and the entire range of students interested in classic examples of experimental design and hypothetico-deductive reasoning." Richard H. Colby, New Biological Books

"...Rappaport is renowned for his biophysical investigations...Each chapter is methodically written..." Edward M. Bonder, BioScience

"...this book provides an opportunity to read about ingenious experiments examining the physical properties of cells." Edward M. Bonder, BioScience

"...Rappaport's intent in writing the book was to develop for the reader a 'broad acquaintance' with the principles of cytokinesis, leading to a sense of wonderment, enjoyment, and curiosity about this fantastic cellular event." Edward M. Bonder, BioScience

"Cytokinesis would make a nice addition to every biologist's library because it is both a useful primer about the cell biology of cytokinesis and a reminder of why many of us became excited by cell and developmental biology." Edward M. Bonder, BioScience

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