Recent developments in artificial intelligence (AI) and genetic engineering/bio-enhancement reflect a deep-seated discontent with humanity’s embodied condition. This discontent is a contemporary variation on the long-standing dualisms that elevate mind/soul/intelligence over bodies and materiality. The (increasingly well-funded) desire to redesign human bodies and the habitats of our world grow out of the same logic that is reflected in an impatience with imperfection, vulnerability, and frustration. The end-result of transhumanism leads to a strange outcome, namely the eclipse, surpassing, and obliteration of the form of humanity itself. As such, transhumanism reflects a refusal to be in bodies and places, and thus is a particularly striking example of humanity’s rejection of its creaturely condition.