from Section 2A - Sexual and Reproductive Healthcare: Contraception
Published online by Cambridge University Press: 16 January 2024
Combined hormonal contraceptives (CHCs) contain a combination of an oestrogen and a progestin. On the European market they are available as a pill, vaginal ring or patch. Researchers recognised decades ago that the oestrogen component in the form of ethinylestradiol (EE) has a significant impact on the coagulation system which causes an increase in the risk of arterial and venous thromboembolic events. To reduce this risk, low-dose CHC have been developed containing ≤ 35 µg of EE. Higher-dose preparations should not be used anymore.
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