To become citizens of the cognisphere, a new generation of students requires a modified intellectual immune system with the social and cultural competencies to rein in technical affordances – a form of anthropotechnic autoimmunity. A liberal arts education that provides coding and machine learning capacity alongside humanistic competency prepares students to perform daily Turing tests on automated systems that have the capacity to learn and evolve, and reflect on how we are interpolated and disciplined by machine cognizers. The computational regime transgresses geopolitical sovereignty, for it predominates traditional governmental structures and systems of control. In the labor market of the computational regime, work follows information – to discrete information hubs and havens where infrastructure and conditions are opportune. The variety of praxes discussed in this article from the extreme ends of the planetary spectrum illustrate computational thinking through scientific breakthroughs such as CRISPR, geopolitical jurisdiction as in the case of Safe Harbor, and control systems exemplified by telematics. Following seminal sources such as N. Katherine Hayles's scholarship on the cognisphere and Benjamin Bratton's notion of the planetary computing stack, this chapter examines how students can engage the world as citizens of the cognisphere rather than 24–7 mercenaries operating an accidental planetary megastructure made of stacks and protocols. To that end, social and cultural competencies of the humanities remain critical, and must step up to the technological issues of our time.