Book contents
- Stahl’s Essential Psychopharmacology
- Additional material
- Stahl’s Essential Psychopharmacology
- Copyright page
- Contents
- Preface to the Fifth Edition
- CME Information
- 1 Chemical Neurotransmission
- 2 Transporters, Receptors, and Enzymes as Targets of Psychopharmacological Drug Action
- 3 Ion Channels as Targets of Psychopharmacological Drug Action
- 4 Psychosis, Schizophrenia, and the Neurotransmitter Networks Dopamine, Serotonin, and Glutamate
- 5 Targeting Dopamine and Serotonin Receptors for Psychosis, Mood, and Beyond: So-Called “Antipsychotics”
- 6 Mood Disorders and the Neurotransmitter Networks Norepinephrine and γ-Aminobutyric Acid (GABA)
- 7 Treatments for Mood Disorders: So-Called “Antidepressants” and “Mood Stabilizers”
- 8 Anxiety, Trauma, and Treatment
- 9 Chronic Pain and Its Treatment
- 10 Disorders of Sleep and Wakefulness and Their Treatment: Neurotransmitter Networks for Histamine and Orexin
- 11 Attention Deficit Hyperactivity Disorder and Its Treatment
- 12 Dementia: Causes, Symptomatic Treatments, and the Neurotransmitter Network Acetylcholine
- 13 Impulsivity, Compulsivity, and Addiction
- Suggested Reading and Selected References
- Index
3 - Ion Channels as Targets of Psychopharmacological Drug Action
Published online by Cambridge University Press: 19 October 2021
Book contents
- Stahl’s Essential Psychopharmacology
- Additional material
- Stahl’s Essential Psychopharmacology
- Copyright page
- Contents
- Preface to the Fifth Edition
- CME Information
- 1 Chemical Neurotransmission
- 2 Transporters, Receptors, and Enzymes as Targets of Psychopharmacological Drug Action
- 3 Ion Channels as Targets of Psychopharmacological Drug Action
- 4 Psychosis, Schizophrenia, and the Neurotransmitter Networks Dopamine, Serotonin, and Glutamate
- 5 Targeting Dopamine and Serotonin Receptors for Psychosis, Mood, and Beyond: So-Called “Antipsychotics”
- 6 Mood Disorders and the Neurotransmitter Networks Norepinephrine and γ-Aminobutyric Acid (GABA)
- 7 Treatments for Mood Disorders: So-Called “Antidepressants” and “Mood Stabilizers”
- 8 Anxiety, Trauma, and Treatment
- 9 Chronic Pain and Its Treatment
- 10 Disorders of Sleep and Wakefulness and Their Treatment: Neurotransmitter Networks for Histamine and Orexin
- 11 Attention Deficit Hyperactivity Disorder and Its Treatment
- 12 Dementia: Causes, Symptomatic Treatments, and the Neurotransmitter Network Acetylcholine
- 13 Impulsivity, Compulsivity, and Addiction
- Suggested Reading and Selected References
- Index
Summary
Many important psychopharmacological drugs target ion channels. The role of ion channels as important regulators of synaptic neurotransmission have been covered in Chapter 1. Here we discuss how targeting these molecular sites causes alterations in synaptic neurotransmission that are linked in turn to the therapeutic actions of various psychotropic drugs. Specifically, we will cover ligand-gated ion channels and voltage-sensitive ion channels as targets of psychopharmacological drug action.
- Type
- Chapter
- Information
- Stahl's Essential PsychopharmacologyNeuroscientific Basis and Practical Applications, pp. 51 - 76Publisher: Cambridge University PressPrint publication year: 2021