This chapter describes the first week of the Russian invasion of Ukraine and the immediate sanctions and export control measures that followed. While focusing on the U.S. response, it describes key steps taken by the European Union, the United Kingdom, Canada, Japan, Australia, and others. The chapter links developments in the ground war to the key economic responses by the forces aligned against Russia. As the extent of the Russian invasion became clear, sanctions were announced and subsequently ratcheted up extremely rapidly. The chapter also highlights the extraordinarily coordinated nature of the sanctions response.