Chapters 6, 7 and 8 cover the use of medication and psychological treatments in the management of violence; the section concludes with a pragmatic chapter on the prevention and management of violence in inpatient settings. When there is a degree of violence that represents a threat to others, medication of some nature is often necessary. The use of medication is fraught with risks, especially when high dosages are considered necessary in difficult cases. Rapid tranquillisation is sometimes necessary and, although there has to be some flexibility in the use of such drugs, it is very important for all practitioners to be aware of the protocols for such management in the settings where they work. Not all protocols are the same, but they are wisely chosen and illustrate the importance of pharmacists’ advice, especially when many drugs have been or are currently being given simultaneously. Polypharmacy can be dangerous.