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from Section 4 - Antepartum (Medical Complications)
Published online by Cambridge University Press: 08 April 2025
Hemoglobinopathies are vast grouping of inherited disorders of the hemoglobin chain genes that affect over 270 million people globally. The most common hemoglobinopathies include sickle cell, alpha- thalassemia, and beta-thalassemia. Each of these diseases has numerous phenotypes and thus presentation and management of each will vary. Generally, the carrier or asymptomatic states have pregnancy outcomes that mirror the general population. Patients with clinically significant disease are at increased risk for numerous maternal and fetal complications. All patients desiring pregnancy and those that are currently pregnant should be screened for hemoglobinopathy and those found to have one provided with genetic counseling regarding any potential maternal or fetal risks.
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