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12 - Ischemic Strokes

from Section 3 - Neurological Emergencies

Published online by Cambridge University Press:  02 November 2023

Kaushal Shah
Affiliation:
Weill Cornell Medical Center, New York
Jarone Lee
Affiliation:
Massachusetts General Hospital, Boston
Clark G. Owyang
Affiliation:
Weill Cornell Medical Center, New York
Benjamin Christian Renne
Affiliation:
Massachusetts General Hospital, Boston
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Summary

  • Cerebrovascular accident (CVA) or stroke is an interruption of blood supply due to thrombosis or embolization.

  • Thrombosis is caused by an in situ clot at a site of atherosclerotic plaque. Embolization is caused by an intravascular embolus. Sources include atrial fibrillation, ventricular aneurysm, hypokinetic ventricle, myocardial infarction, prosthetic valve, infective endocarditis and proximal friable atherosclerotic plaques.

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Publisher: Cambridge University Press
Print publication year: 2023

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References

Demaerschalk, BM, Kleindorfer, DO, Adeoye, OM, et al. Scientific rationale for the inclusion and exclusion criteria for intravenous alteplase in acute ischemic stroke: A statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2016;47(2):581641.CrossRefGoogle ScholarPubMed
Ma, H, Campbell, BC, Parsons, MW, et al. Thrombolysis guided by perfusion imaging up to 9 hours after onset of stroke. New Engl J Med 2019;380(19):17951803.CrossRefGoogle ScholarPubMed
National Institutes of Health. NIH Stroke Scale. Bethesda, MD: National Institutes of Health, National Institute of Neurological Disorders and Stroke; 2013. Available from: http://stroke.nih.gov/documents/NIH_Stroke_Scale.pdf [last accessed February 15, 2023].Google Scholar
Phipps, MS, Cronin, CA. Management of acute ischemic stroke. BMJ 2020;368.Google ScholarPubMed
Powers, WJ. Acute ischemic stroke. New Engl J Med 2020;383(3):252260.CrossRefGoogle ScholarPubMed
Powers, WJ, Rabinstein, AA, Ackerson, T, et al. Guidelines for the early management of patients with acute ischemic stroke: 2019 update to the 2018 guidelines for the early management of acute ischemic stroke: A guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2019;50(12):e344e418.CrossRefGoogle Scholar

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