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Chapter 9 - Neuropsychiatric Consequences of Moderate to Severe Traumatic Brain Injury

Published online by Cambridge University Press:  10 August 2021

Marco Mula
Affiliation:
St George's Hospital Medical School, University of London
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Summary

Moderate to severe traumatic brain injuries commonly present with a wide range of long term emotional and behavioural problems which are often classed as organic neuropsychiatric conditions. These range from mood disorders such as depression, emotional lability, apathy, anxiety disorders such as panic disorder, specific phobia or Post-traumatic stress disorder (PTSD) or long term personality change. These neuropsychiatric co-morbidities influence quality of life and outcomes and cause significant distress to the patient. Hence, accurate and early recognition and appropriate management of these problems is important. Development of post-traumatic epilepsy can further influence neuropsychiatric presentations following moderate to severe brain injury. A range of neuropsychiatric presentations following moderate to severe traumatic brain injury are described and an approach to management is discussed.

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Publisher: Cambridge University Press
Print publication year: 2021

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References

Deb, S., Lyons, I., Koutzoukis, C., Ali, I. and McCarthy, G. 1999. Rate of psychiatric illness 1 year after traumatic brain injury. Am J Psychiatr 156: 374–8.Google Scholar
Koponen, S., Taiminen, T., Portin, R., et al. 2002. Axis I and II psychiatric disorders after traumatic brain injury: a 30-year follow-up study. Am J Psychiatr 159:1315–21.CrossRefGoogle ScholarPubMed
Alway, Y., Gould, K.R., Johnston, L., McKenzie, D. and Ponsford, J. 2016. A prospective examination of Axis I psychiatric disorders in the first 5 years following moderate to severe traumatic brain injury. Psychol Med 46:1331–41.CrossRefGoogle ScholarPubMed
Fann, J.R., Hart, T. and Schomer, K.G. 2009. Treatment for depression after traumatic brain injury: a systematic review. J Neurotrauma 26:2383–402.Google Scholar
Bombardier, C.H., Fann, J.R., Temkin, N.R., Esselman, P.C., Barber, J. and Dikmen, S.S. 2010. Rates of major depressive disorder and clinical outcomes following traumatic brain injury. JAMA, 303:1938–45.Google Scholar
Osborn, A.J., Mathias, J.L. and Fairweather-Schmidt, A.K. 2014. Depression following adult, non-penetrating traumatic brain injury: A meta-analysis examining methodological variables and sample characteristics. Neurosci Biobehav Rev 47:115.Google Scholar
Jorge, R.E. and Starkstein., S.E. 2005. Pathophysiologic aspects of major depression following traumatic brain injury. J Head Trauma Rehabil 20:475–87.CrossRefGoogle ScholarPubMed
Teasdale, T.W. and Engberg, A.W. 2001. Suicide after traumatic brain injury: a population study. J Neurol Neurosurg Psychiatr 71:436–40.CrossRefGoogle ScholarPubMed
Skopp, N.A., Trofimovich, L., Grimes, J., Oetjen-Gerdes, L. and Gahm, G.A. Relations between suicide and traumatic brain injury, psychiatric diagnoses, and relationship problems, active component, US Armed Forces, 2001–2009. Air Force Medical Support Agency Fort Detrick MD Air Force Medical Evaluation Support Activity; 2012 Feb.Google Scholar
Agrawal, N. and Rickards, H. 2011. Detection and treatment of depression in neurological disorders. J Neurol Neurosurg Psychiatr 82:828–9.CrossRefGoogle ScholarPubMed
Cuijpers, P., van Straten, A. and Wamerdam, L. 2007. Problem solving therapies for depression: A meta-analysis. Eur Psychiatry 22:915.CrossRefGoogle ScholarPubMed
Laviolette, V., Ouellet, M.C., Beaulieu-Bonneau, S. and Giguere, M. 2014. Anxiety in the first year after traumatic brain injury: Evolution and risk factors. Brain Injury 28:705–6.Google Scholar
Hiott, D.W. and Labbate, L. 2002. Anxiety disorders associated with traumatic brain injuries. NeuroRehabilitation 17:345–55.CrossRefGoogle ScholarPubMed
Rogers, J.M. and Read, C.A. 2007. Psychiatric comorbidity following traumatic brain injury. Brain Injury 21:1321–33.CrossRefGoogle ScholarPubMed
Tanev, K.S., Pentel, K.Z., Kredlow, M.A. and Charney, M.E. 2014. PTSD and TBI co-morbidity: scope, clinical presentation and treatment options. Brain Injury 28:261–70.Google Scholar
van Reekum, R., Stuss, D.T. and Ostrander, L. 2005. Apathy: why care? J Neuropsychiatry and Clinical Neurosci 17:719.CrossRefGoogle ScholarPubMed
Marin, R.S., Biedrzycki, R.C. and Firinciogullar, S. 1991. Reliability and validity of the Apathy Evaluation Scale. Psychiatry Res 38:143–62.CrossRefGoogle ScholarPubMed
Lane-Brown, A.T. and Tate, R.L. 2009. Apathy after acquired brain impairment: a systematic review of non-pharmacological interventions. Neuropsychol Rehabil 19:481516.Google Scholar
Batty, R.A., Rossell., S.L., Francis, A.J. and Ponsford, J. 2013. Psychosis following traumatic brain injury. Brain Impairment 14:2141.Google Scholar
Fujii, D.E. and Ahmed, I. 2014. Psychotic disorder caused by traumatic brain injury. Psychiatr Clin North Am 37:113–24.Google Scholar
Marshman, L.A., Jakabek, D., Hennessy, M., Quirk, F. and Guazzo, E.P. 2013. Post-traumatic amnesia. J Clin Neurosci 20:1475–81.Google Scholar
Steel, J., Ferguson, A., Spencer, E. and Togher, L. 2015. Language and cognitive communication during post-traumatic amnesia: A critical synthesis. NeuroRehabilitation 37:221–34.CrossRefGoogle ScholarPubMed
Metting, Z., Rödiger, L.A., de Jong, B.M., Stewart, R.E., Kremer, B.P. and van der Naalt J. 2010. Acute cerebral perfusion CT abnormalities associated with posttraumatic amnesia in mild head injury. J Neurotrauma 27:2183–9.Google Scholar
Singh, R., Venkateshwara, G., Nair, K.P., Khan, M. and Saad, R. 2014. Agitation after traumatic brain injury and predictors of outcome. Brain Injury 28:336–40.CrossRefGoogle ScholarPubMed
Shores, E.A., Marosszeky, J.E., Sandanam, J. and Batchelor, J. 1986. Preliminary validation of a scale for measuring the duration of post-traumatic amnesia. Medical J Australia, 144:569–72.Google Scholar
Fleminger, S., Greenwood, R.R. and Oliver, D.L. 2003. Pharmacological management for agitation and aggression in people with acquired brain injury. Cochrane Database of Systematic Reviews. 2006(4):CD003299.Google Scholar
Plantier, D. and Luauté, J. 2016. Drugs for behavior disorders after traumatic brain injury: systematic review and expert consensus leading to French recommendations for good practice. Ann Phys Rehabil Med 59:4257.CrossRefGoogle ScholarPubMed
Warden, D.L., Gordon, B, McAllister, T.W., et al. 2006. Guidelines for the pharmacologic treatment of neurobehavioral sequelae of traumatic brain injury. J Neurotrauma 23:1468501.Google Scholar
Franulic, A., Horta, E., Maturana, R., Scherpenisse, J. and Carbonell, C. 2000. Organic personality disorder after traumatic brain injury: Cognitive, anatomic and psychosocial factors. A 6 month follow-up. Brain Injury 14:431–9.Google Scholar
Hibbard, M.R., Bogdany, J., Uysal, S., et al. 2000. Axis II psychopathology in individuals with traumatic brain injury. Brain Injury 14:4561.CrossRefGoogle ScholarPubMed
Golden, Z. and Golden, C.J. 2003. Impact of brain injury severity on personality dysfunction. Int J Neuroscience 113:73345.CrossRefGoogle ScholarPubMed
Tien, H.C., Tremblay, L.N., Rizoli, S.B., et al. 2006. Association between alcohol and mortality in patients with severe traumatic head injury. Arch Surg 141:1185–91.Google Scholar
Mathias, J.L. and Osborn, A.J. 2018. Impact of day-of-injury alcohol consumption on outcomes after traumatic brain injury: A meta-analysis. Neuropsychol Rehabil 28:9971018.CrossRefGoogle ScholarPubMed
Opreanu, R.C., Kuhn, D. and Basson, M.D. 2010. Influence of alcohol on mortality in traumatic brain injury. J Am Coll Surg 210:9971007.CrossRefGoogle ScholarPubMed
Allen, S., Stewart, S.H., Cusimano, M. and Asbridge, M. 2016. Examining the relationship between traumatic brain injury and substance use outcomes in the Canadian population. Subst Use Misuse 51:1577–86.Google Scholar
Mazzini, L., Cossa, F.M., Angelino, E., Campini, R., Pastore, I. and Monaco, F. 2003. Posttraumatic epilepsy: neuroradiologic and neuropsychological assessment of long-term outcome. Epilepsia 44:569–74.Google Scholar
Mula, M. 2019. Psychiatric aspects of posttraumatic epilepsy: A still unexplored area. Epilepsy Behav 101:106598.Google Scholar
Rapoport, M.J., McCullagh, S., Shammi, P. and Feinstein, A. 2005. Cognitive impairment associated with major depression following mild and moderate traumatic brain injury. J Neuropsychiatry Clin Neurosci 17:61–5CrossRefGoogle ScholarPubMed
Westbrook, L.E., Devinsky, O. and Geocadin, R. 1998. Nonepileptic seizures after head injury. Epilepsia 39:978–82.Google Scholar
Barry, E., Krumholz, A., Bergey, G.K., Chatha, H., Alemayehu, S. and Grattan, L. 1998. Nonepileptic posttraumatic seizures. Epilepsia 39:427–31.Google Scholar

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