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Chapter 7 - Applied Pharmacokinetic Models

from Section I - Basic Principles

Published online by Cambridge University Press:  26 February 2021

Tom Peck  and
Benjamin Harris
Tom Peck
Affiliation:
Royal Hampshire County Hospital, Winchester and University Hospital Southampton
Benjamin Harris
Affiliation:
Hampshire Hospitals NHS Trust
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Summary

In the previous chapter we explored the mathematical principles and models that can be used to predict plasma concentrations of drugs, particularly compartment models. This chapter will discuss the use of drugs for which commercial infusion devices are available that are programmed with kinetic models, in particular propofol and remifentanil.

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Pharmacology for Anaesthesia and Intensive Care , pp. 68 - 79
Publisher: Cambridge University Press
Print publication year: 2021

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