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Chapter 9 - Ancillary Tests

from Section IV - Neoplastic Disorders of Bone Marrow

Published online by Cambridge University Press:  25 January 2024

By
Bradford Siegele ,
Liming Bao ,
Amy L. Treece  and
Xiayuan Liang
Edited by
Xiayuan Liang ,
Bradford Siegele  and
Jennifer Picarsic
Xiayuan Liang
Affiliation:
Children’s Hospital of Colorado
Bradford Siegele
Affiliation:
Children’s Hospital of Colorado
Jennifer Picarsic
Affiliation:
Cincinnati Childrens Hospital Medicine Center
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Summary

Hematolymphoid malignancies represent an area in which ancillary studies offer particularly valuable information for diagnosis, classification, and prognosis, as well as risk-stratified and targeted therapy. The results of multiple test modalities, including flow cytometry, immunohistochemistry, and cytogenetic and molecular genetic analyses, should be integrated and interpreted within the context of morphologic evaluation. In this chapter, the principles, general technical aspects, and clinical applications of these ancillary tests are discussed.

Type
Chapter
Information
Pediatric Pathology of Hematopoietic and Histiocytic Disorders , pp. 97 - 120
Publisher: Cambridge University Press
Print publication year: 2024

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