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Chapter 60 - Hepatitis B and C Virus Infections in Pregnancy

from Section 11 - Infectious Conditions in Pregnancy

Published online by Cambridge University Press:  23 February 2023

By
Amira El-Messidi  and
Maged Peter Ghali
Edited by
Amira El-Messidi  and
Alan D. Cameron
Amira El-Messidi
Affiliation:
McGill University, Montréal
Alan D. Cameron
Affiliation:
University of Glasgow
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Summary

You are seeing a new patient in consultation for transfer of care to your high-risk obstetrics unit at a tertiary center. She is a 27-year-old primigravida at 14+3 weeks’ gestation with an incidentally positive surface antigen to the hepatitis B virus (HBsAg) on routine prenatal testing. A copy of the original laboratory report has been provided to you. Although detailed serological investigations were performed, results are not available. The patient is aware of the results. Referral to a hepatologist has also been instigated. The patient’s first-trimester sonogram and aneuploidy screen were unremarkable. She has no obstetric complaints.

Keywords

Hepatitis B virus infection, hepatitis C virus infection, pregnancyClinical manifestationsComorbiditiesPhysical examinationInvestigationsPrenatal screening, serology analysisInvasive diagnostic procedures, considerationsCounselingTreatment, tenofovir fumaratePerinatal risks, complications, maternal-fetal morbidity, adverse outcomeMother-to-child, perinatal transmissionAntepartum, intrapartum, postpartum managementObstetric deliveryPercutaneous exposure, hepatitis B infection
Type
Chapter
Information
OSCEs in Obstetrics and Maternal-Fetal Medicine
An Evidence-Based Approach
 , pp. 774 - 786
Publisher: Cambridge University Press
Print publication year: 2023

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References

Primary Sources

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Secondary Sources

ACOG Practice Advisory: Routine hepatitis C virus screening in pregnant individuals. May 2021. Available at www.acog.org/clinical/clinical-guidance/practice-advisory/articles/2021/05/routine-hepatitis-c-virus-screening-in-pregnant-individuals. Accessed October 26, 2021.Google Scholar
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US Preventive Services Task Force Recommendation Statement. Screening for Hepatitis C Virus Infection in Adolescents and Adults. JAMA 2020;323(10):970–975.CrossRefGoogle Scholar

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