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10 - Using Comparative Genomics to Resolve the Origin and Early Evolution of Snakes

from Part III - Genomic Perspectives

Published online by Cambridge University Press:  30 July 2022

By
Sara Ruane  and
Jeffrey W. Streicher
Edited by
David J. Gower  and
Hussam Zaher
David J. Gower
Affiliation:
Natural History Museum, London
Hussam Zaher
Affiliation:
Universidade de São Paulo
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Summary

Despite recent advances, key events in snake evolution have remained difficult to resolve, including their position in the squamate tree and several ingroup relationships. Comparative genomics has unrealised potential for phylogenetic inference and may advance understanding of snake evolution. This chapter reviews the history of snake molecular phylogenetics up to the current genomics revolution. This work has often corroborated phylogenetic inferences from morphology but also discovered relationships not previously considered or supported. We discuss properties of snake nuclear genomes, considering their potential for phylogenetic inference. Using data from 30 available squamate genomes, we provide preliminary examples applying both cumulative and non-cumulative frequency coding to genome size, GC content, and 14 repetitive element characteristics. Cumulative frequency coding outperforms non-cumulative coding and recovers most, but not all, well-known snake clades. We describe how the relationships of some snake lineages remains poorly supported despite their inclusion in large genomic-scale datasets, and suggest possible avenues of future research using comparative genomics.

Keywords

phylogenysystematicsSquamatamoleculesgenomesphylogenomicshistoryevolution
Type
Chapter
Information
The Origin and Early Evolutionary History of Snakes , pp. 209 - 234
Publisher: Cambridge University Press
Print publication year: 2022

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