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Section 3 - Lifestyle, Environment, and Optimizing Reproduction in the 40s

Published online by Cambridge University Press:  15 September 2022

Dimitrios S. Nikolaou
Affiliation:
Chelsea and Westminster Hospital, London
David B. Seifer
Affiliation:
Yale Reproductive Medicine, New Haven, CT
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Publisher: Cambridge University Press
Print publication year: 2022

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References

Hassan, MAM, Killick, SR. Negative lifestyle is associated with a significant reduction in fecundity. Fertil Steril. 2004;81(2):384–92.Google Scholar
Skogsdal, Y, Fadl, H, Cao, Y, Karlsson, J, Tydén, T. An intervention in contraceptive counseling increased the knowledge about fertility and awareness of preconception health-a randomized controlled trial. Ups J Med Sci. 2019;124(3):203–12.CrossRefGoogle ScholarPubMed
Hammiche, F, Laven, JSE, van Mil, N, de Cock, M, de Vries, JH, Lindemans, J, et al. Tailored preconceptional dietary and lifestyle counselling in a tertiary outpatient clinic in the Netherlands. Hum Reprod. 2011;26(9):2432–41.CrossRefGoogle Scholar
van der Steeg, JW, Steures, P, Eijkemans, MJ, Habbema, JD, Hompes, PG, Burggraaff, JM, et al. Obesity affects spontaneous pregnancy chances in subfertile, ovulatory women. Hum Reprod. 2008;23(2):324–8.Google Scholar
Giviziez, CR, Sanchez, EGM, Approbato, MS, Maia, MCS, Fleury, EAB, Sasaki, RSA. Obesity and anovulatory infertility: a review. JBRA Assist Reprod. 2016;20(4):240–5.Google Scholar
Zaidi, S, Usmani, A, Shokh, IS, Alam, SE. Ovarian reserve and BMI between fertile and subfertile women. J Coll Physicians Surg Pak. 2009;19(1):21–4.Google Scholar
Villareal, DT, Apovian, CM, Kushner, RF, Klein, S. Obesity in older adults: technical review and position statement of the American Society for Nutrition and NAASO, The Obesity Society. Am J Clin Nutr. 2005;82(5):923–34.CrossRefGoogle ScholarPubMed
Poblete, JA, Olmos, P. Obesity and gestational diabetes in pregnant care and clinical practice. Curr Vasc Pharmacol. 2021;19(2):154–64.Google Scholar
Lopez-Jaramillo, P, Barajas, J, Rueda-Quijano, SM, Lopez-Lopez, C, Felix, C. Obesity and preeclampsia: common pathophysiological mechanisms. Front Physiol. 2018;9:1838.Google Scholar
Sirimi, N, Goulis, DG. Obesity in pregnancy. Hormones. 2010;9(4):299306.Google Scholar
Yogev, Y, Catalano, PM. Pregnancy and obesity. Obstet Gynecol Clin North Am. 2009;36(2):285300.CrossRefGoogle ScholarPubMed
Best, D, Avenell, A, Bhattacharya, S. How effective are weight-loss interventions for improving fertility in women and men who are overweight or obese? A systematic review and meta-analysis of the evidence. Hum Reprod Update. 2017;23(6):681705.Google Scholar
Grodstein, F, Goldman, MB, Cramer, DW. Body mass index and ovulatory infertility. Epidemiology. 1994;5(2):247–50.Google Scholar
Freizinger, M, Franko, DL, Dacey, M, Okun, B, Domar, AD. The prevalence of eating disorders in infertile women. Fertil Steril. 2010;93(1):72–8.Google Scholar
Micali, N, Martini, MG, Thomas, JJ, Eddy, KT, Kothari, R, Russell, E, et al. Lifetime and 12-month prevalence of eating disorders amongst women in mid-life: a population-based study of diagnoses and risk factors. BMC Med. 2017;15(1):12.Google Scholar
Boutari, C, Pappas, PD, Mintziori, G, Nigdelis, MP, Athanasiadis, L, Goulis, DG, et al. The effect of underweight on female and male reproduction. Metabolism. 2020;107:154229.Google Scholar
Rodino, IS, Byrne, SM, Sanders, KA. Eating disorders in the context of preconception care: fertility specialists’ knowledge, attitudes, and clinical practices. Fertil Steril. 2017;107(2):494501.Google Scholar
Lucas, C, Charlton, KE, Yeatman, H. Nutrition advice during pregnancy: do women receive it and can health professionals provide it? Matern Child Health J. 2014;18(10):2465–78.CrossRefGoogle Scholar
Chiu, Y-H, Chavarro, JE, Souter, I. Diet and female fertility: doctor, what should I eat? Fertil Steril. 2018;110(4):560–9.CrossRefGoogle ScholarPubMed
Toledo, E, Lopez-del Burgo, C, Ruiz-Zambrana, A, Donazar, M, Navarro-Blasco, Í, Martínez-González, MA, et al. Dietary patterns and difficulty conceiving: a nested case–control study. Fertil Steril. 2011;96(5):1149–53.Google Scholar
Bodnar, LM, Siega-Riz, AM. A Diet Quality Index for Pregnancy detects variation in diet and differences by sociodemographic factors. Public Health Nutr. 2002;5(6):801–9.Google Scholar
Vieira, A, Taucher, S. Maternal age and neural tube defects: evidence for a greater effect in spina bifida than in anencephaly. Revista médica de Chile. 2005;133:6270.Google Scholar
Tamura, T, Picciano, MF. Folate and human reproduction. Am J Clin Nutr. 2006;83(5):9931016.Google Scholar
Ebisch, I, Thomas, C, Peters, W, Braat, D, Steegers-Theunissen, R. The importance of folate, zinc and antioxidants in the pathogenesis and prevention of subfertility. Hum Reprod Update. 2007;13(2):163–74.CrossRefGoogle ScholarPubMed
Navot, D, Bergh, RA, Williams, MA, Garrisi, GJ, Guzman, I, Sandler, B, et al. Poor oocyte quality rather than implantation failure as a cause of age-related decline in female fertility. Lancet. 1991;337(8754):1375–7.Google Scholar
Grineva, EN, Karonova, T, Micheeva, E, Belyaeva, O, Nikitina, IL. Vitamin D deficiency is a risk factor for obesity and diabetes type 2 in women at late reproductive age. Aging (Albany NY). 2013;5(7):575–81.Google Scholar
Zhao, J, Huang, X, Xu, B, Yan, Y, Zhang, Q, Li, Y. Whether vitamin D was associated with clinical outcome after IVF/ICSI: a systematic review and meta-analysis. Reprod Biol Endocrinol. 2018;16(1):13.Google Scholar
Parikh, G, Varadinova, M, Suwandhi, P, Araki, T, Rosenwaks, Z, Poretsky, L, et al. Vitamin D regulates steroidogenesis and insulin-like growth factor binding protein-1 (IGFBP-1) production in human ovarian cells. Horm Metab Res. 2010;42(10):754–7.CrossRefGoogle ScholarPubMed
Rudick, BJ, Ingles, SA, Chung, K, Stanczyk, FZ, Paulson, RJ, Bendikson, KA. Influence of vitamin D levels on in vitro fertilization outcomes in donor-recipient cycles. Fertil Steril. 2014;101(2):447–52.Google Scholar
Javaid, MK, Crozier, SR, Harvey, NC, Gale, CR, Dennison, EM, Boucher, BJ, et al. Maternal vitamin D status during pregnancy and childhood bone mass at age 9 years: a longitudinal study. Lancet. 2006;367(9504):3643.CrossRefGoogle ScholarPubMed
Sasaki, H, Hamatani, T, Kamijo, S, Iwai, M, Kobanawa, M, Ogawa, S, et al. Impact of oxidative stress on age-associated decline in oocyte developmental competence. Front Endocrinol (Lausanne). 2019;10(811).Google Scholar
Ruder, EH, Hartman, TJ, Reindollar, RH, Goldman, MB. Female dietary antioxidant intake and time to pregnancy among couples treated for unexplained infertility. Fertil Steril. 2014;101(3):759–66.Google Scholar
Mier-Cabrera, J, Genera-García, M, De la Jara-Díaz, J, Perichart-Perera, O, Vadillo-Ortega, F, Hernández-Guerrero, C. Effect of vitamins C and E supplementation on peripheral oxidative stress markers and pregnancy rate in women with endometriosis. Int J Gynecol Obstet. 2008;100(3):252–6.Google Scholar
Showell, MG, Mackenzie-Proctor, R, Jordan, V, Hart, RJ. Antioxidants for female subfertility. Cochrane Database Syst Rev. 2017;7(7):Cd007807.Google Scholar
Ben-Meir, A, Kim, K, McQuaid, R, Esfandiari, N, Bentov, Y, Casper, RF, et al. Co-enzyme Q10 supplementation rescues cumulus cells dysfunction in a maternal aging model. Antioxidants (Basel). 2019;8(3).Google Scholar
Özcan, P, Fıçıcıoğlu, C, Kizilkale, O, Yesiladali, M, Tok, OE, Ozkan, F, et al. Can coenzyme Q10 supplementation protect the ovarian reserve against oxidative damage? J Assist Reprod Genet. 2016;33(9):1223–30.CrossRefGoogle ScholarPubMed
Miles, EA, Noakes, PS, Kremmyda, LS, Vlachava, M, Diaper, ND, Rosenlund, G, et al. The Salmon in Pregnancy Study: study design, subject characteristics, maternal fish and marine n-3 fatty acid intake, and marine n-3 fatty acid status in maternal and umbilical cord blood. Am J Clin Nutr. 2011;94(6 Suppl):1986s-92s.Google Scholar
Nehra, D, Le, HD, Fallon, EM, Carlson, SJ, Woods, D, White, YA, et al. Prolonging the female reproductive lifespan and improving egg quality with dietary omega-3 fatty acids. Aging Cell. 2012;11(6):1046–54.Google Scholar
Al-Safi, ZA, Liu, H, Carlson, NE, Chosich, J, Harris, M, Bradford, AP, et al. Omega-3 fatty acid supplementation lowers serum FSH in normal weight but not obese women. J Clin Endocrinol Metab. 2016;101(1):324–33.Google Scholar
Kermack, AJ, Lowen, P, Wellstead, SJ, Fisk, HL, Montag, M, Cheong, Y, et al. Effect of a 6-week “Mediterranean” dietary intervention on in vitro human embryo development: the Preconception Dietary Supplements in Assisted Reproduction double-blinded randomized controlled trial. Fertil Steril. 2020;113(2):260–9.Google Scholar
Dizdar, OS, Baspınar, O, Kocer, D, Dursun, ZB, Avcı, D, Karakükcü, C, et al. Nutritional risk, micronutrient status and clinical outcomes: a prospective observational study in an infectious disease clinic. Nutrients. 2016;8(3):124.Google Scholar
Grieger, JA, Grzeskowiak, LE, Wilson, RL, Bianco-Miotto, T, Leemaqz, SY, Jankovic-Karasoulos, T, et al. Maternal selenium, copper and zinc concentrations in early pregnancy, and the association with fertility. Nutrients. 2019;11(7):1609.Google Scholar
Mintziori, G, Mousiolis, A, Duntas, LH, Goulis, DG. Evidence for a manifold role of selenium in infertility. Hormones (Athens). 2020;19(1):55–9.Google Scholar
Ramos, SB, Stumpo, DJ, Kennington, EA, Phillips, RS, Bock, CB, Ribeiro-Neto, F, et al. The CCCH tandem zinc-finger protein Zfp36l2 is crucial for female fertility and early embryonic development. Development. 2004;131(19):4883–93.Google Scholar
Qin, JC, Fan, L, Qin, AP. The effect of dehydroepiandrosterone (DHEA) supplementation on women with diminished ovarian reserve (DOR) in IVF cycle: Evidence from a meta-analysis. J Gynecol Obstet Hum Reprod. 2017;46(1):17.CrossRefGoogle ScholarPubMed
Liu, Y, Hu, L, Fan, L, Wang, F. Efficacy of dehydroepiandrosterone (DHEA) supplementation for in vitro fertilization and embryo transfer cycles: a systematic review and meta-analysis. Gynecol Endocrinol. 2018;34(3):178–83.CrossRefGoogle ScholarPubMed
Çelik, Ö, Acet, M, İmren, A, Çelik, N, Erşahin, A, Aktun, LH, et al. DHEA supplementation improves endometrial HOXA-10 mRNA expression in poor responders. J Turk Ger Gynecol Assoc. 2017;18(4):160–6.Google Scholar
Practice Committee of the American Society for Reproductive Medicine. Smoking and infertility: a committee opinion. Fertil Steril. 2018;110(4):611–8.Google Scholar
Ozbakir, B, Tulay, P. Does cigarette smoking really have a clinical effect on folliculogenesis and oocyte maturation? Zygote. 2020;28(4):318–21.Google Scholar
de Angelis, C, Nardone, A, Garifalos, F, Pivonello, C, Sansone, A, Conforti, A, et al. Smoke, alcohol and drug addiction and female fertility. Reprod Biol Endocrinol. 2020;18(1):21.Google Scholar
Lyngsø, J, Ramlau-Hansen, CH, Bay, B, Ingerslev, HJ, Strandberg-Larsen, K, Kesmodel, US. Low-to-moderate alcohol consumption and success in fertility treatment: a Danish cohort study. Hum Reprod. 2019;34(7):1334–44.Google Scholar
Hawkins Bressler, L, Bernardi, LA, De Chavez, PJ, Baird, DD, Carnethon, MR, Marsh, EE. Alcohol, cigarette smoking, and ovarian reserve in reproductive-age African-American women. Am J Obstet Gynecol. 2016;215(6):758.e1-.e9.Google Scholar
Jensen, TK, Hjollund, NH, Henriksen, TB, Scheike, T, Kolstad, H, Giwercman, A, et al. Does moderate alcohol consumption affect fertility? Follow up study among couples planning first pregnancy. BMJ. 1998;317(7157):505–10.Google Scholar
Gaskins, AJ, Chavarro, JE. Diet and fertility: a review. Am J Obstet Gynecol. 2018;218(4):379–89.Google Scholar
Zhang, X, Liu, X, Chen, L, Wu, DY, Nie, ZW, Gao, YY, et al. Caffeine delays oocyte aging and maintains the quality of aged oocytes safely in mouse. Oncotarget. 2017;8(13):20602–11.Google Scholar
Mena, GP, Mielke, GI, Brown, WJ. Do physical activity, sitting time and body mass index affect fertility over a 15-year period in women? Data from a large population-based cohort study. Hum Reprod. 2020;35(3):676–83.Google Scholar
Gudmundsdottir, SL, Flanders, WD, Augestad, LB. Physical activity and fertility in women: the North-Trøndelag Health Study. Hum Reprod. 2009;24(12):3196–204.Google Scholar
Morris, SN, Missmer, SA, Cramer, DW, Powers, RD, McShane, PM, Hornstein, MD. Effects of lifetime exercise on the outcome of in vitro fertilization. Obstet Gynecol. 2006;108(4):938–45.Google Scholar
Catov, JM, Parker, CB, Gibbs, BB, Bann, CM, Carper, B, Silver, RM, et al. Patterns of leisure-time physical activity across pregnancy and adverse pregnancy outcomes. Int J Behav Nutr Phys Act. 2018;15(1):68.Google Scholar
Pivarnik, JM, Chambliss, HO, Clapp, JF, Dugan, SA, Hatch, MC, Lovelady, CA, et al. Impact of physical activity during pregnancy and postpartum on chronic disease risk. Med Sci Sports Exerc. 2006;38(5):9891006.Google Scholar
Blümel, JE, Cano, A, Mezones-Holguín, E, Barón, G, Bencosme, A, Benítez, Z, et al. A multinational study of sleep disorders during female mid-life. Maturitas. 2012;72(4):359–66.Google Scholar
Hollander, LE, Freeman, EW, Sammel, MD, Berlin, JA, Grisso, JA, Battistini, M. Sleep quality, estradiol levels, and behavioral factors in late reproductive age women. Obstet Gynecol. 2001;98(3):391–7.Google Scholar
Willis, SK, Hatch, EE, Wesselink, AK, Rothman, KJ, Mikkelsen, EM, Wise, LA. Female sleep patterns, shift work, and fecundability in a North American preconception cohort study. Fertil Steril. 2019;111(6):1201–10.e1.Google Scholar
Wang, I-D, Liu, Y-L, Peng, C-K, Chung, C-H, Chang, S-Y, Tsao, C-H, et al. Non-apnea sleep disorder increases the risk of subsequent female infertility—a nationwide population-based cohort study. Sleep. 2017;41(1).Google Scholar
Stocker, LJ, Macklon, NS, Cheong, YC, Bewley, SJ. Influence of shift work on early reproductive outcomes: a systematic review and meta-analysis. Obstet Gynecol. 2014;124(1):99110.Google Scholar
Goldstein, CA, Smith, YR. Sleep, circadian rhythms, and fertility. Curr Sleep Med Rep. 2016;2(4):206–17.Google Scholar
Vgontzas, AN, Zoumakis, E, Bixler, EO, Lin, H-M, Follett, H, Kales, A, et al. Adverse effects of modest sleep restriction on sleepiness, performance, and inflammatory cytokines. J Clin Endocrinol Metab. 2004;89(5):2119–26.Google Scholar
von Känel, R, Dimsdale, JE, Ancoli‐Israel, S, Mills, PJ, Patterson, TL, McKibbin, CL, et al. Poor sleep is associated with higher plasma proinflammatory cytokine interleukin‐6 and procoagulant marker fibrin D‐dimer in older caregivers of people with Alzheimer’s disease. J Am Geriatr Soc. 2006;54(3):431–7.Google Scholar
Okun, ML, Coussons-Read, M, Hall, M. Disturbed sleep is associated with increased C-reactive protein in young women. Brain Behav Immun. 2009;23(3):351–4.CrossRefGoogle ScholarPubMed
Alijotas-Reig, J, Esteve-Valverde, E, Ferrer-Oliveras, R, Llurba, E, Gris, JM. Tumor necrosis factor-alpha and pregnancy: focus on biologics. An updated and comprehensive review. Clin Rev Allergy Immunol. 2017;53(1):4053.Google Scholar
Gica, N, Panaitescu, AM, Iancu, G, Botezatu, R, Peltecu, G, Gica, C. The role of biological markers in predicting infertility associated with non-obstructive endometriosis. Ginekol Pol. 2020;91(4):189–92.CrossRefGoogle ScholarPubMed
Kloss, JD, Perlis, ML, Zamzow, JA, Culnan, EJ, Gracia, CR. Sleep, sleep disturbance, and fertility in women. Sleep Med Rev. 2015;22:7887.Google Scholar
Pal, L, Bevilacqua, K, Zeitlian, G, Shu, J, Santoro, N. Implications of diminished ovarian reserve (DOR) extend well beyond reproductive concerns. Menopause. 2008;15(6).Google Scholar
Mo, L, Mansfield, DR, Joham, A, Cain, SW, Bennett, C, Blumfield, M, et al. Sleep disturbances in women with and without polycystic ovary syndrome in an Australian National Cohort. Clin Endocrinol. 2019;90(4):570–8.Google Scholar
Green, A, Cohen-Zion, M, Haim, A, Dagan, Y. Evening light exposure to computer screens disrupts human sleep, biological rhythms, and attention abilities. Chronobiol Int. 2017;34(7):855–65.Google Scholar
Willis, SK, Hatch, EE, Wise, LA. Sleep and female reproduction. Curr Opin Obstet Gynecol. 2019;31(4):222–7.Google Scholar
Fallahzadeh, H, Zareei Mahmood Abadi, H, Momayyezi, M, Malaki Moghadam, H, Keyghobadi, N. The comparison of depression and anxiety between fertile and infertile couples: a meta-analysis study. Int J Reprod Biomed (Yazd). 2019;17(3):153–62.Google Scholar
Szkodziak, F, Krzyżanowski, J, Szkodziak, P. Psychological aspects of infertility. A systematic review. J Int Med Res. 2020;48(6):0300060520932403.Google Scholar
Lynch, CD, Sundaram, R, Maisog, JM, Sweeney, AM, Buck Louis, GM. Preconception stress increases the risk of infertility: results from a couple-based prospective cohort study—the LIFE study. Hum Reprod. 2014;29(5):1067–75.Google Scholar
Patel, A, Sharma, PSVN, Kumar, P. Application of mindfulness-based psychological interventions in infertility. J Hum Reprod Sci. 2020;13(1):321.Google Scholar
Chow, KM, Cheung, MC, Cheung, IK. Psychosocial interventions for infertile couples: a critical review. J Clin Nurs. 2016;25(15–16):2101–13.Google Scholar
Morgan, N, Christensen, K, Skedros, G, Kim, S, Schliep, K. Life stressors, hypertensive disorders of pregnancy, and preterm birth. J Psychosom Obstet Gynaecol. 2020:19.Google Scholar
Hobel, CJ, Goldstein, AMY, Barrett, ES. Psychosocial stress and pregnancy outcome. Clin Obstet Gynecol. 2008;51(2).Google Scholar
Wiegner, L, Hange, D, Björkelund, C, Ahlborg, G. Prevalence of perceived stress and associations to symptoms of exhaustion, depression and anxiety in a working age population seeking primary care – an observational study. BMC Fam Pract. 2015;16(1):38.Google Scholar
Schanche, E, Vøllestad, J, Binder, P-E, Hjeltnes, A, Dundas, I, Nielsen, GH. Participant experiences of change in mindfulness-based stress reduction for anxiety disorders. Int J Qual Stud Health Well-being. 2020;15(1):1776094.Google Scholar
Li, J, Long, L, Liu, Y, He, W, Li, M. Effects of a mindfulness-based intervention on fertility quality of life and pregnancy rates among women subjected to first in vitro fertilization treatment. Behav Res Ther. 2016;77:96104.Google Scholar
Dhillon, A, Sparkes, E, Duarte, RV. Mindfulness-based interventions during pregnancy: a systematic review and meta-analysis. Mindfulness (N Y). 2017;8(6):1421–37.Google ScholarPubMed
Duncan, LG, Cohn, MA, Chao, MT, Cook, JG, Riccobono, J, Bardacke, N. Benefits of preparing for childbirth with mindfulness training: a randomized controlled trial with active comparison. BMC Pregnancy Childbirth. 2017;17(1):140.Google Scholar
Muthukrishnan, S, Jain, R, Kohli, S, Batra, S. Effect of mindfulness meditation on perceived stress scores and autonomic function tests of pregnant Indian women. J Clin Diagn Res. 2016;10(4):CC058.Google Scholar
Smith, JF, Eisenberg, ML, Millstein, SG, Nachtigall, RD, Shindel, AW, Wing, H, et al. The use of complementary and alternative fertility treatment in couples seeking fertility care: data from a prospective cohort in the United States. Fertil Steril. 2010;93(7):2169–74.Google Scholar
Miner, SA, Robins, S, Zhu, YJ, Keeren, K, Gu, V, Read, SC, et al. Evidence for the use of complementary and alternative medicines during fertility treatment: a scoping review. BMC Complement Altern Med. 2018;18(1):158.Google Scholar

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