Published online by Cambridge University Press: 26 January 2024
Myopathies are a group of clinical diseases that impair the function of skeletal muscle. The muscle fibers are affected directly, as the innervation and neuromuscular junctions remain intact. Although a primary symptom is often weakness, variable patterns of stiffness, contractures, or cramping may also be present. These symptoms are often exacerbated by the physiologic stress of pregnancy and labor, which may unmask a previously undiagnosed myopathy. The hereditary myopathies include muscular dystrophies, congenital myopathies, metabolic myopathies, and disorders of muscle membrane excitability. Inflammatory myopathies are a subset of acquired myopathy. Each classification has specific obstetric and anesthetic considerations, which will be described in detail.
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