from Section 2 - Clinical Neurosurgical Diseases
Published online by Cambridge University Press: 04 January 2024
Radiculopathy refers to pathology at the nerve root level, manifest as positive symptoms such as pain, paresthesias and dysesthesias, and negative symptoms such as numbness and weakness. While a number of causes for radiculopathy exist, the archetypal etiology is lumbar disc herniation, leading to compression of the traversing or, less commonly, exiting nerve root. Such mechanical bases for radiculopathy were first recognized nearly a century ago, initially in the lumbar region by Mixter and Barr(1934),followed by the cervical spine by Semmes and Murphey in 1943.
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