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Chapter 8 - Prognostication in Neuroinfectious Disease

from Part I - Disease-Specific Prognostication

Published online by Cambridge University Press:  14 November 2024

David M. Greer
Affiliation:
Boston University School of Medicine and Boston Medical Center
Neha S. Dangayach
Affiliation:
Icahn School of Medicine at Mount Sinai and Mount Sinai Health System
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Summary

Patients with neurological infections are often critically ill, requiring cardiopulmonary support and prolonged admission to the Neurointensive Care Unit (Neuro-ICU). In recent years, the pathogens and manifestations of neurological infections have expanded in the setting of both immunosuppressive medications and globalization. Despite advances in antimicrobial therapy, however, the morbidity and mortality of these infections remains high. Outcomes following neurological infections are variable, determined by host factors, pathogen factors, and the specific syndrome. In this chapter, we will review outcomes following neurological infections of the central nervous system (CNS) in critically ill patients, focusing on the most commonly encountered diagnoses, including meningitis, abscess, and encephalitis.

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Publisher: Cambridge University Press
Print publication year: 2024

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