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Case 31 - Myasthenia Gravis with Acetylcholine Receptor Antibodies (AChR MG)

from Disorders of the Neuromuscular Junction

Published online by Cambridge University Press:  aN Invalid Date NaN

Jessica E. Hoogendijk
Affiliation:
University Medical Center Utrecht
Marianne de Visser
Affiliation:
Amsterdam University Medical Center
Pieter A. van Doorn
Affiliation:
Erasmus MC, University Medical Center, Rotterdam
Erik H. Niks
Affiliation:
Leiden University Medical Center
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Summary

A 70-year-old woman was referred by her GP because of progressive nasal speech and difficulties with chewing and swallowing, shortly after abdominal surgery because of a borderline malignant cystoadenofibroma of the uterus. Weeks later, she also noticed drooping of both eyelids and a tendency for her head to drop at the end of a day. In retrospect, mild nasal speech had been present for some months prior to surgery.

Type
Chapter
Information
Neuromuscular Disease
A Case-Based Approach
, pp. 157 - 160
Publisher: Cambridge University Press
Print publication year: 2024

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References

Suggested Reading

Doughty, CT, Guidon, AC. Diagnostic testing for ocular myasthenia gravis: stronger together. Neurology 2020;95(13):563564. doi: 10.1212/WNL.0000000000010616. Epub 2020 Aug 11. PMID: 32788244.CrossRefGoogle Scholar
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Vanoli, F, Mantegazza, R. Current drug treatment of myasthenia gravis. Curr Opin Neurol 2023;36(5):410415. doi: 10.1097/WCO.0000000000001196. Epub 2023 Aug 30. PMID: 37678337.CrossRefGoogle ScholarPubMed
Verschuuren, JJ, Palace, J, Murai, H, et al. Advances and ongoing research in the treatment of autoimmune neuromuscular junction disorders. Lancet Neurol 2022;21(2):189202. doi: 10.1016/S1474-4422(21)00463-4. Erratum in: Lancet Neurol 2022 Mar;21(3):e3. PMID: 35065041.CrossRefGoogle ScholarPubMed

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