Book contents
- The Neurology Riddle Book
- Series page
- The Neurology Riddle Book
- Copyright page
- Dedication
- Contents
- Foreword
- Preface
- 1
- 2
- 3
- 4
- 5
- 6
- 7
- 8
- 9
- 10
- 11
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- Index
25
Published online by Cambridge University Press: 21 November 2024
Book contents
- The Neurology Riddle Book
- Series page
- The Neurology Riddle Book
- Copyright page
- Dedication
- Contents
- Foreword
- Preface
- 1
- 2
- 3
- 4
- 5
- 6
- 7
- 8
- 9
- 10
- 11
- 12
- 13
- 14
- 15
- 16
- 17
- 18
- 19
- 20
- 21
- 22
- 23
- 24
- 25
- 26
- 27
- 28
- 29
- 30
- 31
- 32
- 33
- 34
- 35
- 36
- 37
- 38
- 39
- 40
- 41
- 42
- 43
- 44
- 45
- 46
- 47
- 48
- 49
- 50
- 51
- 52
- 53
- 54
- 55
- 56
- 57
- 58
- 59
- 60
- 61
- 62
- 63
- 64
- 65
- 66
- 67
- 68
- 69
- 70
- 71
- 72
- 73
- 74
- 75
- 76
- 77
- 78
- 79
- 80
- 81
- 82
- 83
- 84
- 85
- 86
- 87
- 88
- 89
- 90
- 91
- 92
- 93
- 94
- 95
- 96
- 97
- 98
- 99
- 100
- 101
- 102
- 103
- 104
- 105
- 106
- 107
- 108
- 109
- 110
- 111
- 112
- 113
- 114
- 115
- 116
- 117
- 118
- 119
- 120
- 121
- 122
- 123
- 124
- 125
- 126
- 127
- 128
- 129
- 130
- 131
- 132
- 133
- 134
- 135
- 136
- 137
- 138
- 139
- 140
- 141
- 142
- 143
- 144
- 145
- 146
- 147
- 148
- 149
- 150
- Index
Summary
Huntington disease (HD) is an autosomal dominant neurodegenerative disease resulting from the trinucleotide repeat expansion of (CAG) sequence on chromosome 4, HTT gene, in exon 1. These CAG trinucleotide repeats (<35 repeats) are seen in individuals without HD, though all individuals with ≥40 CAG repeats develop HD, and those with ≥60 often develop juvenile HD. The average age of onset is 35–45 years.
- Type
- Chapter
- Information
- The Neurology Riddle Book150 Common and Rare Neurological Diseases in Riddle Form, pp. 75 - 78Publisher: Cambridge University PressPrint publication year: 2024