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Published online by Cambridge University Press:  21 November 2024

James Dolbow
Affiliation:
University Hospitals Cleveland Medical Center
Neel Fotedar
Affiliation:
University Hospitals Cleveland Medical Center
Joshua Edmondson
Affiliation:
University Hospital Cleveland Medical Centter
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Summary

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy CADASIL and its recessively inherited version CARASIL are cerebral small-vessel diseases caused by missense mutation in the NOTCH 3 gene located on chromosome 19. Interestingly, this locus is the same as seen in familial hemiplegic migraine, and migraine is the first symptom these patients experience in ~40% of cases in Caucasians. However, migraine prevalence varies widely based on ethnic background, occurring less commonly in those of Asian heritage.

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The Neurology Riddle Book
150 Common and Rare Neurological Diseases in Riddle Form
, pp. 309 - 312
Publisher: Cambridge University Press
Print publication year: 2024

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  • 100
  • James Dolbow, University Hospitals Cleveland Medical Center, Neel Fotedar, University Hospitals Cleveland Medical Center, Joshua Edmondson, University Hospital Cleveland Medical Centter
  • Book: The Neurology Riddle Book
  • Online publication: 21 November 2024
  • Chapter DOI: https://doi.org/10.1017/9781009527378.102
Available formats
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  • 100
  • James Dolbow, University Hospitals Cleveland Medical Center, Neel Fotedar, University Hospitals Cleveland Medical Center, Joshua Edmondson, University Hospital Cleveland Medical Centter
  • Book: The Neurology Riddle Book
  • Online publication: 21 November 2024
  • Chapter DOI: https://doi.org/10.1017/9781009527378.102
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • 100
  • James Dolbow, University Hospitals Cleveland Medical Center, Neel Fotedar, University Hospitals Cleveland Medical Center, Joshua Edmondson, University Hospital Cleveland Medical Centter
  • Book: The Neurology Riddle Book
  • Online publication: 21 November 2024
  • Chapter DOI: https://doi.org/10.1017/9781009527378.102
Available formats
×