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Chapter 5 - Differential Diagnosis

Published online by Cambridge University Press:  10 February 2021

Carlos A. Perez ,
Andrew Smith  and
Flavia Nelson
By
Carlos A. Pérez
Carlos A. Perez
Affiliation:
University of Texas, Houston
Andrew Smith
Affiliation:
OhioHealth Riverside Methodist Hospital in Columbus, Ohio, USA
Flavia Nelson
Affiliation:
University of Minnesota, Minneapolis
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Summary

Despite recent refinements in the diagnostic criteria, multiple sclerosis (MS) remains a challenging diagnosis. Several acquired and inherited disorders can mimic MS both clinically and radiographically, which may further complicate the diagnostic process. This chapter focuses on the most common diseases that mimic MS (“MS mimics”), the most relevant clinical and diagnostic characteristics suggestive of an alternative diagnosis, and the best diagnostic workup for the exclusion of similar conditions. A discussion of specific magnetic resonance imaging (MRI) features that may help distinguish MS from its mimics is presented in Chapter 6.

Type
Chapter
Information
Multiple Sclerosis
A Practical Manual for Hospital and Outpatient Care
 , pp. 59 - 80
Publisher: Cambridge University Press
Print publication year: 2021

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