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4 - Reactive Conditions and Other Diseases Where Flow Cytometric Findings May Mimic Haematological Malignancies

Published online by Cambridge University Press:  01 February 2018

Anna Porwit
Affiliation:
Lunds Universitet, Sweden
Marie Christine Béné
Affiliation:
Université de Nantes, France
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Publisher: Cambridge University Press
Print publication year: 2018

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References

Craig, FE and Foon, KA. Flow cytometric immunophenotyping for hematologic neoplasms. Blood; 111 (2008):3941–67.CrossRefGoogle ScholarPubMed
Davis, BH, Holden, JT, Bene, MC, et al. 2006 Bethesda International Consensus recommendations on the flow cytometric immunophenotypic analysis of hematolymphoid neoplasia: medical indications. Cytometry B Clin Cytom; 72 Suppl 1 (2007):S5S13.CrossRefGoogle ScholarPubMed
Johansson, U, Bloxham, D, Couzens, S, et al. British Committee for Standards in. Guidelines on the use of multicolour flow cytometry in the diagnosis of haematological neoplasms. British Committee for Standards in Haematology. Br J Haematol; 165 (2014):455–88.CrossRefGoogle ScholarPubMed
Arber, DA, Orazi, A, Hasserjian, R, et al. The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood; 127 (2016):2391–405.CrossRefGoogle Scholar
Kern, W, Haferlach, C, Schnittger, S, and Haferlach, T. Clinical utility of multiparameter flow cytometry in the diagnosis of 1013 patients with suspected myelodysplastic syndrome: correlation to cytomorphology, cytogenetics, and clinical data. Cancer; 116 (2010):4549–63.CrossRefGoogle ScholarPubMed
Himmelmann, A, Gautschi, O, Nawrath, M, et al. Persistent polyclonal B-cell lymphocytosis is an expansion of functional IgD(+)CD27(+) memory B cells. Br J Haematol; 114 (2001):400–5.CrossRefGoogle ScholarPubMed
Cornet, E, Mossafa, H, Courel, K, Lesesve, JF, and Troussard, X. Persistent polyclonal binucleated B-cell lymphocytosis and MECOM gene amplification. BMC Res Notes; 9 (2016):138.CrossRefGoogle ScholarPubMed
Mossafa, H, Malaure, H, Maynadie, M, et al. Persistent polyclonal B lymphocytosis with binucleated lymphocytes: a study of 25 cases. Groupe Francais d'Hematologie Cellulaire. Br J Haematol; 104 (1999):486–93.CrossRefGoogle ScholarPubMed
Lima, M, Teixeira Mdos, A, Queiros, ML, et al. Immunophenotype and TCR-Vbeta repertoire of peripheral blood T-cells in acute infectious mononucleosis. Blood Cells Mol Dis; 30 (2003):112.CrossRefGoogle ScholarPubMed
Moon, Y, Jang, WR, Yi, HG, et al. Klebsiella pneumoniae associated extreme plasmacytosis. Infect Chemother; 45 (2013):435–40.CrossRefGoogle ScholarPubMed
Gawoski, JM and Ooi, WW. Dengue fever mimicking plasma cell leukemia. Arch Pathol Lab Med; 127 (2003):1026–7.CrossRefGoogle ScholarPubMed
Kumar, S, Kimlinger, T, and Morice, W. Immunophenotyping in multiple myeloma and related plasma cell disorders. Best Pract Res Clin Haematol; 23 (2010):433–51.CrossRefGoogle ScholarPubMed
Davis, BH, Olsen, SH, Ahmad, E, and Bigelow, NC. Neutrophil CD64 is an improved indicator of infection or sepsis in emergency department patients. Arch Pathol Lab Med; 130 (2006):654–61.CrossRefGoogle ScholarPubMed
Arnoulet, C, Bene, MC, Durrieu, F, et al. Four- and five-color flow cytometry analysis of leukocyte differentiation pathways in normal bone marrow: a reference document based on a systematic approach by the GTLLF and GEIL. Cytometry B Clin Cytom; 78 (2010):410.CrossRefGoogle ScholarPubMed
Cossarizza, A, De Biasi, S, Gibellini, L, et al. Cytometry, immunology, and HIV infection: three decades of strong interactions. Cytometry A; 83 (2013):680–91.Google ScholarPubMed
Ouyang, J, Zheng, W, Shen, Q, et al. Flow cytometry immunophenotypic analysis of Philadelphia-negative myeloproliferative neoplasms: correlation with histopathologic features. Cytometry B Clin Cytom; 88 (2015):236–43.CrossRefGoogle ScholarPubMed
Orazi, A. Histopathology in the diagnosis and classification of acute myeloid leukemia, myelodysplastic syndromes, and myelodysplastic/myeloproliferative diseases. Pathobiology; 74 (2007):97114.CrossRefGoogle ScholarPubMed
Porwit, A, Fend, F, Kremer, M, et al. Issues in diagnosis of small B cell lymphoid neoplasms involving the bone marrow and peripheral blood. Report on the Bone Marrow Workshop of the XVIIth meeting of the European Association for Haematopathology and the Society for Hematopathology. Histopathology; 69 (2016):349–73.CrossRefGoogle Scholar
Maciejewski, JP, Hibbs, JR, Anderson, S, Katevas, P, and Young, NS. Bone marrow and peripheral blood lymphocyte phenotype in patients with bone marrow failure. Exp Hematol; 22 (1994):1102–10.Google ScholarPubMed
Risitano, AM, Kook, H, Zeng, W, et al. Oligoclonal and polyclonal CD4 and CD8 lymphocytes in aplastic anemia and paroxysmal nocturnal hemoglobinuria measured by V beta CDR3 spectratyping and flow cytometry. Blood; 100 (2002):178–83.CrossRefGoogle ScholarPubMed
Lu, T, Liu, Y, Li, P, et al. Decreased circulating Th22 and Th17 cells in patients with aplastic anemia. Clin Chim Acta; 450 (2015):90–6.CrossRefGoogle ScholarPubMed
de Latour, RP, Visconte, V, Takaku, T, et al. Th17 immune responses contribute to the pathophysiology of aplastic anemia. Blood; 116 (2010):4175–84.CrossRefGoogle Scholar
Manz, CY, Nissen, C, and Wodnar-Filipowicz, A. Deficiency of CD34+ c-kit+ and CD34+38- hematopoietic precursors in aplastic anemia after immunosuppressive treatment. Am J Hematol; 52 (1996):264–74.3.0.CO;2-Q>CrossRefGoogle ScholarPubMed
Maciejewski, JP, Anderson, S, Katevas, P, and Young, NS. Phenotypic and functional analysis of bone marrow progenitor cell compartment in bone marrow failure. Br J Haematol; 87 (1994):227–34.CrossRefGoogle ScholarPubMed
Huang, M, Li, J, Zhao, G, et al. Immunophenotype of myeloid granulocytes: a pilot study for distinguishing myelodysplastic syndrome and aplastic anemia by flow cytometry. Int J Lab Hematol; 32 (2010):275–81.CrossRefGoogle ScholarPubMed
Sevilla, DW, Emmons, FN, Colovai, AI, et al. Hematogones are markedly reduced in pediatric acquired aplastic anemia: multiparametric flow cytometric analysis. Leuk Lymphoma; 50 (2009):1951–7.CrossRefGoogle ScholarPubMed
Young, NS, Maciejewski, JP, Sloand, E, et al. The relationship of aplastic anemia and PNH. Int J Hematol; 76 Suppl 2 (2002):168–72.CrossRefGoogle ScholarPubMed
Borowitz, MJ, Craig, FE, Digiuseppe, JA, et al. Guidelines for the diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria and related disorders by flow cytometry. Cytometry B Clin Cytom; 78 (2010):211–30.Google ScholarPubMed
Sutherland, DR, Illingworth, A, Keeney, M, and Richards, SJ. High-sensitivity detection of PNH red blood cells, red cell precursors, and white blood cells. Curr Protoc Cytom; 72 (2015):130.Google ScholarPubMed
Sutherland, DR, Kuek, N, Davidson, J, et al. Diagnosing PNH with FLAER and multiparameter flow cytometry. Cytometry B Clin Cytom; 72 (2007):167–77.Google ScholarPubMed
Raza, A, Ravandi, F, Rastogi, A, et al. A prospective multicenter study of paroxysmal nocturnal hemoglobinuria cells in patients with bone marrow failure. Cytometry B Clin Cytom; 86 (2014):175–82.CrossRefGoogle ScholarPubMed
Loken, MR, Chu, SC, Fritschle, W, Kalnoski, M, and Wells, DA. Normalization of bone marrow aspirates for hemodilution in flow cytometric analyses. Cytometry B Clin Cytom; 76 (2009):2736.CrossRefGoogle ScholarPubMed
Aldawood, AM, Kinkade, Z, Rosado, FG, et al. A novel method to assess bone marrow purity is useful in determining blast percentage by flow cytometry in acute myeloid leukemia and myelodysplasia. Ann Hematol Oncol; 2 (2015):pii 1038.Google ScholarPubMed
Delgado, JA, Guillen-Grima, F, Moreno, C, et al. A simple flow-cytometry method to evaluate peripheral blood contamination of bone marrow aspirates. J Immunol Methods; 442 (2017):54–8.CrossRefGoogle ScholarPubMed
Muroi, K, Fujiwara, S, Tatara, R, et al. CD56 expression in normal immature granulocytes after allogeneic hematopoietic stem cell transplantation. J Clin Exp Hematop; 53 (2013):247–50.CrossRefGoogle ScholarPubMed
Xu, Y, McKenna, RW, Karandikar, NJ, Pildain, AJ, and Kroft, SH. Flow cytometric analysis of monocytes as a tool for distinguishing chronic myelomonocytic leukemia from reactive monocytosis. Am J Clin Pathol; 124 (2005):799806.CrossRefGoogle ScholarPubMed
Kern, W, Danhauser-Riedl, S, Ratei, R, et al. Detection of minimal residual disease in unselected patients with acute myeloid leukemia using multiparameter flow cytometry for definition of leukemia-associated immunophenotypes and determination of their frequencies in normal bone marrow. Haematologica; 88 (2003):646–53.Google ScholarPubMed
Curtis, BR. Drug-induced immune neutropenia/agranulocytosis. Immunohematology; 30 (2014):95101.CrossRefGoogle ScholarPubMed
Bourre-Tessier, J and Haraoui, B. Methotrexate drug interactions in the treatment of rheumatoid arthritis: a systematic review. J Rheumatol; 37 (2010):1416–21.CrossRefGoogle ScholarPubMed
Curtis, BR. Drug-induced immune thrombocytopenia: incidence, clinical features, laboratory testing, and pathogenic mechanisms. Immunohematology; 30 (2014):5565.CrossRefGoogle ScholarPubMed
Tomer, A. Flow cytometry for the diagnosis of autoimmune thrombocytopenia. Curr Hematol Rep; 5 (2006):64–9.Google ScholarPubMed
Zhao, Y, Zhu, M, Jiang, M, et al. An improved flow cytometric immunobead array to detect autoantibodies in plasma from patients with immune thrombocytopenic purpura. Clin Chim Acta; 438 (2015):396400.CrossRefGoogle ScholarPubMed
King, MJ, Behrens, J, Rogers, C, et al. Rapid flow cytometric test for the diagnosis of membrane cytoskeleton-associated haemolytic anaemia. Br J Haematol; 111 (2000):924–33.Google ScholarPubMed
Singleton, BK, Ahmed, M, Green, CA, et al. CD44 as a potential screening marker for preliminary differentiation between congenital dyserythropoietic anemia type II and hereditary spherocytosis. Cytometry B Clin Cytom (2016).Google ScholarPubMed
Thedsawad, A, Taka, O, and Wanachiwanawin, W. Significances of red cell bound immunoglobulin G as detected by flow cytometry in patients with Coombs-negative immune hemolysis. Transfus Med; 26 (2016):130–7.CrossRefGoogle ScholarPubMed
Steensma, DP. Dysplasia has A differential diagnosis: distinguishing genuine myelodysplastic syndromes (MDS) from mimics, imitators, copycats and impostors. Curr Hematol Malig Rep; 7 (2012):310–20.CrossRefGoogle Scholar
Malcovati, L and Cazzola, M. The shadowlands of MDS: idiopathic cytopenias of undetermined significance (ICUS) and clonal hematopoiesis of indeterminate potential (CHIP). Hematology Am Soc Hematol Educ Program; 2015 (2015):299307.CrossRefGoogle ScholarPubMed
Steensma, DP, Bejar, R, Jaiswal, S, et al. Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes. Blood; 126 (2015):916.CrossRefGoogle ScholarPubMed

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