Pictures are two-dimensional depictive representations. They include static pictures and animations. The latter are defined as pictorial displays that change their structure or other features over time and trigger perception of a continuous change. Static and animated pictures can display static as well as dynamic content. Both can have an envisioning, explanatory, orientation, organizing, and argumentative function. Picture comprehension entails sub-semantic perceptual processing, semantic perceptual processing, and conceptual processing. Sub-semantic perceptual processing is primarily pre-attentive and data-driven. It results in viewer-cantered and object-cantered visual representations. Semantic perceptual processing is attentive and data- as well as knowledge-driven. It results in object or event recognition. Conceptual processing is attentive and primarily knowledge-driven. It creates complex propositional structures and mental models in working memory. Picture comprehension is based on analog structure mapping under the guidance of perceptual and conceptual representations.