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Rivastigmine

Published online by Cambridge University Press:  20 February 2025

K. Ray Chaudhuri
Affiliation:
King's College London
Peter Jenner
Affiliation:
King's College London
Valentina Leta
Affiliation:
King's College London
Shelley Jones
Affiliation:
King's College London
Iro Boura
Affiliation:
St. George General Hospital of Chania, Crete, Greece
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Summary

Rivastigmine ([3-[(1S)-1-(dimethylamino)ethyl]phenyl]N-ethyl-N-methylcarbamate) can be found as an off-white to slightly yellow powder in oral formulations or a viscous, clear, and colourless to yellow to very slightly brown liquid in transdermal formulations. It has a molecular weight of 250.34 (as the base) and an empirical formula of C14H22N2O2.

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Publisher: Cambridge University Press
Print publication year: 2025

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References

Suggested Reading

Burn, D, Emre, M, McKeith, I, De Deyn, PP, Aarsland, D, Hsu, C, Lane, R. Effects of rivastigmine in patients with and without visual hallucinations in dementia associated with Parkinson’s disease. Mov Disord 2006; 21(11): 18991907.CrossRefGoogle ScholarPubMed
Devos, D, Moreau, C, Maltête, D, Lefaucheur, R, Kreisler, A, Eusebio, A, Defer, G, Ouk, T, Azulay, JP, Krystkowiak, P, Witjas, T, Dalliaux, M, Destée, A, Duhamel, A, Bordt, R, Defebvre, L, Dujardin, K. Rivastigmine in apathetic but dementia and depression-free patients with Parkinson’s disease: a double-blind, placebo-controlled, randomised clinical trial. J Neurol Neurosurg Psychiatry 2014; 85(6): 668674.CrossRefGoogle ScholarPubMed
Di Giacopo, R, Fasano, A, Quaranta, D, Della Marca, G, Bove, F, Bentiglio, AR. Rivastigmine as alternative treatment for refractory REM behavior disorder in Parkinson’s disease. Mov Disord 2012; 27(4): 559561.CrossRefGoogle ScholarPubMed
Emre, M, Poewe, W, De Deyn, PP, Barone, P, Kulisevsky, J, Pourcher, E, van Laar, T, Storch, A, Micheli, F, Burn, D, Durif, F, Pahwa, R, Callegari, F, Tenenbaum, N, Strohmaier, C. Long-term safety of rivastigmine in Parkinson disease dementia: an open-label, randomized study. Clin Neuropharmacol 2014; 37(1): 916.CrossRefGoogle ScholarPubMed
Henderson, EJ, Lord, SR, Brodie, MA, Gaunt, DM, Lawrence, AD, Close, JCT, Whone, AL, Ben-Shlomo, Y. Rivastigmine for gait stability in patients with Parkinson’s disease (ReSPonD): a randomised, double-blind, placebo-controlled, phase 2 trial. Lancet Neurol 2016; 15(3): 249258.CrossRefGoogle ScholarPubMed
Mamikonyan, E, Xie, SX, Melvin, E, Weintraub, D. Rivastigmine for mild cognitive impairment in Parkinson disease: a placebo-controlled study. Mov Disord 2015; 30(7): 912918.CrossRefGoogle ScholarPubMed

References

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  • Rivastigmine
  • K. Ray Chaudhuri, King's College London, Peter Jenner, King's College London, Valentina Leta, King's College London, Shelley Jones, King's College London, Iro Boura, St. George General Hospital of Chania, Crete, Greece
  • Book: The Movement Disorders Prescriber's Guide to Parkinson's Disease
  • Online publication: 20 February 2025
  • Chapter DOI: https://doi.org/10.1017/9781009222648.042
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  • Rivastigmine
  • K. Ray Chaudhuri, King's College London, Peter Jenner, King's College London, Valentina Leta, King's College London, Shelley Jones, King's College London, Iro Boura, St. George General Hospital of Chania, Crete, Greece
  • Book: The Movement Disorders Prescriber's Guide to Parkinson's Disease
  • Online publication: 20 February 2025
  • Chapter DOI: https://doi.org/10.1017/9781009222648.042
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Rivastigmine
  • K. Ray Chaudhuri, King's College London, Peter Jenner, King's College London, Valentina Leta, King's College London, Shelley Jones, King's College London, Iro Boura, St. George General Hospital of Chania, Crete, Greece
  • Book: The Movement Disorders Prescriber's Guide to Parkinson's Disease
  • Online publication: 20 February 2025
  • Chapter DOI: https://doi.org/10.1017/9781009222648.042
Available formats
×