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Oxybutynin

Published online by Cambridge University Press:  20 February 2025

K. Ray Chaudhuri
Affiliation:
King's College London
Peter Jenner
Affiliation:
King's College London
Valentina Leta
Affiliation:
King's College London
Shelley Jones
Affiliation:
King's College London
Iro Boura
Affiliation:
St. George General Hospital of Chania, Crete, Greece
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Summary

Oxybutynin (4-diethylaminobut-2-ynyl 2-cyclohexyl-2-phenylglycolate; 4-(diethylamino)-2-butynyl α-phenylcyclohexaneglycolic acid ester) has a molecular weight of 357.5 and a molecular formula of C22H31NO3.

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Publisher: Cambridge University Press
Print publication year: 2025

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References

Suggested Reading

Herschorn, S, Stothers, L, Carlson, K, Egerdie, B, Gajewski, JB, Pommerville, P, Schulz, J, Radomski, S, Drutz, H, Barkin, J, Paradiso-Hardy, F. Tolerability of 5 mg solifenacin once daily versus 5 mg oxybutynin immediate release 3 times daily: results of the VECTOR trial. J Urol 2010; 183(5): 18921898.CrossRefGoogle ScholarPubMed
Wagg, A, Dale, M, Tretter, R, Stow, B, Compion, G. Randomised, multicentre, placebo-controlled, double-blind crossover study investigating the effect of solifenacin and oxybutynin in elderly people with mild cognitive impairment: the SENIOR study. Eur Urol 2013; 64(1): 7481.CrossRefGoogle ScholarPubMed

References

AHFS Drug information, 2012. Bethesda: American Society of Health-System Pharmacists. Accessed on 31 December 2022 via www.medicinescomplete.com.Google Scholar
Buser, N, Ivic, S, Kessler, TM, Kessels, AG, Bachmann, LM. Efficacy and adverse events of antimuscarinics for treating overactive bladder: network meta-analyses. Eur Urol, 2012; 62(6): 10401060.CrossRefGoogle ScholarPubMed
Joint Formulary Committee. British National Formulary (online). London: BMJ Group and Pharmaceutical Press. Accessed on 31 December 2022 via www.medicinescomplete.com.Google Scholar
Kessler, TM, Bachmann, LM, Minder, C, Löhrer, D, Umbehr, M, Schünemann, HJ, Kessels, AG. Adverse event assessment of antimuscarinics for treating overactive bladder: a network meta-analytic approach. PLoS One 2011; 6(2): e16718.CrossRefGoogle Scholar
Oxybutynin. In: Brayfield, A (Ed.), Martindale: The Complete Drug Reference. London: The Royal Pharmaceutical Society of Great Britain. Accessed on 31 December 2022 via www.medicinescomplete.com.Google Scholar
Oxybutynin. In: DRUGDEX® System (electronic version). Truven Health Analytics, Greenwood Village, Colorado, USA. Accessed on 31 December 2022 via www.micromedexsolutions.com.Google Scholar
Summary of product characteristics – Ditropan 2.5 mg tablets. Neon Healthcare Ltd. Electronic Medicines Compendium: Ditropan 2.5 mg tablets – summary of product characteristics (SmPC) – (emc). Accessed on 31 December 2022 via www.medicines.org.uk.Google Scholar
Vouri, SM, Kebodeaux, CD, Stranges, PM, Teshome, BF. Adverse events and treatment discontinuations of antimuscarinics for the treatment of overactive bladder in older adults: a systematic review and meta-analysis. Arch Gerontol Geriatr 2017; 69: 7796.CrossRefGoogle ScholarPubMed
Wagg, A, Gibson, W, Ostaszkiewicz, J, Johnson, T 3rd, Markland, A, Palmer, MH, Kuchel, G, Szonyi, G, Kirschner-Hermanns, R. Urinary incontinence in frail elderly persons: report from the 5th International Consultation on Incontinence. Neurourol Urodyn 2015; 34(5): 398406.CrossRefGoogle ScholarPubMed
Welk, B, McClure, JA. The impact of anticholinergic use for overactive bladder on cognitive changes in adults with normal cognition, mild cognitive impairment, or dementia. Eur Urol Open Sci 2022; 46: 2229.CrossRefGoogle Scholar
Yoo, DS, Han, JY, Lee, KS, Choo, MS. Prescription pattern of oxybutynin ER in patients with overactive bladder in real life practice: a multicentre, open-label, prospective observational study. Int J Clin Pract 2012; 66(2): 132138.CrossRefGoogle Scholar

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  • Oxybutynin
  • K. Ray Chaudhuri, King's College London, Peter Jenner, King's College London, Valentina Leta, King's College London, Shelley Jones, King's College London, Iro Boura, St. George General Hospital of Chania, Crete, Greece
  • Book: The Movement Disorders Prescriber's Guide to Parkinson's Disease
  • Online publication: 20 February 2025
  • Chapter DOI: https://doi.org/10.1017/9781009222648.036
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  • Oxybutynin
  • K. Ray Chaudhuri, King's College London, Peter Jenner, King's College London, Valentina Leta, King's College London, Shelley Jones, King's College London, Iro Boura, St. George General Hospital of Chania, Crete, Greece
  • Book: The Movement Disorders Prescriber's Guide to Parkinson's Disease
  • Online publication: 20 February 2025
  • Chapter DOI: https://doi.org/10.1017/9781009222648.036
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Oxybutynin
  • K. Ray Chaudhuri, King's College London, Peter Jenner, King's College London, Valentina Leta, King's College London, Shelley Jones, King's College London, Iro Boura, St. George General Hospital of Chania, Crete, Greece
  • Book: The Movement Disorders Prescriber's Guide to Parkinson's Disease
  • Online publication: 20 February 2025
  • Chapter DOI: https://doi.org/10.1017/9781009222648.036
Available formats
×